Evidence map›Paper›PMID 36984828›Full record

ArticleMetabolites2023

Integrated Omics Approach to Discover Differences in the Metabolism of a New Tibetan

Jinhu Wang, Junyu Chen, Dongdong Zhang, Xiaomei Cui, Jinna Zhou, Jing Li, Yanli Wei, Duo Bu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jinhu WangCollege of Ecological Environment, Tibet University, 10 East Zangda Road, Lhasa 850000, China.ORCID 0000-0003-1887-3507
Junyu ChenCollege of Ecological Environment, Tibet University, 10 East Zangda Road, Lhasa 850000, China.
Dongdong ZhangHunan Eco-Geological Survey and Monitoring Institute, 256 Shaoshan North Road, Yuhua District, Changsha 410000, China.
Xiaomei CuiCollege of Ecological Environment, Tibet University, 10 East Zangda Road, Lhasa 850000, China.
Jinna ZhouCollege of Ecological Environment, Tibet University, 10 East Zangda Road, Lhasa 850000, China.
Jing LiCollege of Ecological Environment, Tibet University, 10 East Zangda Road, Lhasa 850000, China.
Yanli WeiCollege of Ecological Environment, Tibet University, 10 East Zangda Road, Lhasa 850000, China.
Duo BuCollege of Ecological Environment, Tibet University, 10 East Zangda Road, Lhasa 850000, China.
Tibet University · CN

Funding

"High level talents" training program for Postgraduates of Tibet University. 2020 - GSP - B013Research on environmental risk management and control of industrial solid waste recycling process in low temperature, low pressure and anoxic environment, which was funded by Sub project of major R&D plan of the Ministry of science and technology. 2019YFC190410304The central government supports the phased achievement funding of local university projects. ZCKJZ [2022] No. 1, [2021] No.1, [2020] No. 1 and [2019] No. 44The second Comprehensive Scientific investigation and research project on the Qinghai-Tibet Plateau. 2019QZKK0603
6 · The paper itself

Abstract

Microalgae are now widely applied in municipal (YH_3) and industrial sewage (YH_4) treatments. Through integrated omics analysis, we studied the similarities and differences at the molecular level between the two different types of sewage treatment processes. The most significantly enriched gene ontology (GO) terms in both types of sewage treatments were the ribosome, photosynthesis, and proteasome pathways. The results show that the pathways of differentially expressed genes (DEGs) and differentially accumulated metabolites (DAMs) were enriched for photosynthesis, glyoxylate and dicarboxylate metabolism, and carbon fixation in photosynthetic organisms. Considering YH_3 vs. YH_4, the metabolism of citrate, sedoheptulose-7P, and succinate was significantly upregulated. In addition, the results showed that the pathways of DEGs and DAMs were enriched in terms of amino acid metabolism and carotenoid biosynthesis in YH_4 vs. YH_3. The metabolism of S-Adenosyl-L-homocysteine was significantly downregulated, 2-oxobutanoate was significantly upregulated and downregulated, and the metabolism of abscisic acid glucose ester (ABA-GE) was also significantly upregulated. Overall, the results of this paper will help to improve the basic knowledge of the molecular response of microalgae to sewage treatments, and help design a response strategy based on microalgae for complex, mixed sewage treatments.

Indexed as

heavy metal sewage treatmentmetabolomicsmunicipal sewage treatmentTibetan Desmodesmus sp.transcriptomics

Identifiers

PMID36984828
PMCPMC10058882
OpenAlexW4323314109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.