ArticleMetabolites2023
Life-Threatening Cardiogenic Shock Related to Venlafaxine Poisoning-A Case Report with Metabolomic Approach.
Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Therapeutic drug monitoring-guided management of venlafaxine overdose in an adolescent: a case report.Journal of analytical toxicology · 2026Article
- Hexahydrocannabinol-induced rhabdomyolysis and acute kidney injury: a case report combining comprehensive toxicokinetic and metabolomic investigations.Journal of cannabis research · 2026Article
- Case Report: Dynamic characteristics of myocardial depression after severe bupivacaine-induced local anesthetic systemic toxicity.Frontiers in cardiovascular medicine · 2026Article
- Comparison of the Metabolic Profiles Associated with Protonitazene and Protonitazepyne in Two Severe Poisonings.Metabolites · 2025Article
- Cardiotoxicity Associated with Venlafaxine-Defining Features in a Series of Five Cases and a Call for Proactive Monitoring.Journal of clinical medicine · 2025Article
- Management and toxicological analysis of ocular hypertension after EyeCeeBMC ophthalmology · 2024Article
- Pro-active drug-facilitated crimes (DFC): a study in the Department of Forensic Medicine of Paris, France.International journal of legal medicine · 2024Article
- Simultaneously discovering the fate and biochemical effects of pharmaceuticals through untargeted metabolomics.Nature communications · 2023Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolomics in clinical toxicology aim at reliably identifying and semi-quantifying a broad array of endogenous and exogenous metabolites using dedicated analytical methods. Here, we developed a three-step-based workflow to investigate the metabolic impact of the antidepressant drug venlafaxine in a poisoned patient who developed life-threatening cardiac failure managed with extracorporeal membrane oxygenation. Both targeted quantitative and untargeted semi-quantitative metabolomic analyses using liquid chromatography hyphenated to high-resolution tandem mass spectrometry were performed to determine the plasma kinetics of venlafaxine,
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Registered trials
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