Evidence map›Paper›PMID 36984787›Full record

ReviewMetabolites2023

GABA Metabolism, Transport and Their Roles and Mechanisms in the Regulation of Abiotic Stress (Hypoxia, Salt, Drought) Resistance in Plants.

Ding Yuan, Xiaolei Wu, Binbin Gong, Ruixiao Huo, Liran Zhao, Jingrui Li, Guiyun Lü, Hongbo Gao

Open access · goldAbstract readReview
In one paragraph

Review in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
35.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 90 citations in OpenAlex.

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  10. Genes · 2026
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  20. Multi-Omics Analysis Reveals the Regulation of Amino Acid Biosynthesis inInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ding YuanCollaborative Innovation Center of Vegetable Industry in Hebei, Key Laboratory of North China Water-Saving Irrigation Engineering, College of Horticulture, Hebei Agricultural University, Baoding 071000, China.
Xiaolei WuCollaborative Innovation Center of Vegetable Industry in Hebei, Key Laboratory of North China Water-Saving Irrigation Engineering, College of Horticulture, Hebei Agricultural University, Baoding 071000, China.
Binbin GongCollaborative Innovation Center of Vegetable Industry in Hebei, Key Laboratory of North China Water-Saving Irrigation Engineering, College of Horticulture, Hebei Agricultural University, Baoding 071000, China.
Ruixiao HuoCollaborative Innovation Center of Vegetable Industry in Hebei, Key Laboratory of North China Water-Saving Irrigation Engineering, College of Horticulture, Hebei Agricultural University, Baoding 071000, China.
Liran ZhaoCollaborative Innovation Center of Vegetable Industry in Hebei, Key Laboratory of North China Water-Saving Irrigation Engineering, College of Horticulture, Hebei Agricultural University, Baoding 071000, China.
Jingrui LiCollaborative Innovation Center of Vegetable Industry in Hebei, Key Laboratory of North China Water-Saving Irrigation Engineering, College of Horticulture, Hebei Agricultural University, Baoding 071000, China.
Guiyun LüCollaborative Innovation Center of Vegetable Industry in Hebei, Key Laboratory of North China Water-Saving Irrigation Engineering, College of Horticulture, Hebei Agricultural University, Baoding 071000, China.ORCID 0000-0002-6641-1481
Hongbo GaoCollaborative Innovation Center of Vegetable Industry in Hebei, Key Laboratory of North China Water-Saving Irrigation Engineering, College of Horticulture, Hebei Agricultural University, Baoding 071000, China.ORCID 0000-0001-5740-9278
Hebei Agricultural University · CN

Funding

Natural Science Foundation of Hebei Province;the Key Research and Develop Program of Hebei;Hebei Facility vegetables Innovation Team of Modern Agro-industry Technology C2021204006;21326903D;HBCT2021030213
6 · The paper itself

Abstract

γ- Aminobutyric acid (GABA) is a ubiquitous four-carbon non-protein amino acid. In plants, GABA is found in different cell compartments and performs different metabolic functions. As a signalling molecule, GABA participates in the regulation of tolerance to various abiotic stresses. Many research studies have found that GABA accumulates in large amounts when plants are subjected to abiotic stress, which have been demonstrated through the Web of Science, PubMed, Elsevier and other databases. GABA enhances the tolerance of plants to abiotic stress by regulating intracellular pH, ion transport, activating antioxidant systems and scavenging active oxygen species. In the process of GABA playing its role, transport is very important for the accumulation and metabolism pathway of GABA in cells. Therefore, the research on the transport of GABA across the cell membrane and the organelle membrane by transport proteins is a direction worthy of attention. This paper describes the distribution, biosynthesis and catabolism of GABA in plants. In addition, we focus on the latest progress in research on the transport of exogenous GABA and on the function and mechanism in the regulation of the abiotic stress response. Based on this summary of the role of GABA in the resistance to various abiotic stresses, we conclude that GABA has become an effective compound for improving plant abiotic tolerance.

Indexed as

biosynthesis and catabolismdistributionplant growth and developmenttransporter from intracellular and extracellularγ- aminobutyric acid

Identifiers

PMID36984787
PMCPMC10051757
OpenAlexW4322501996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.