Evidence map›Paper›PMID 36984698›Full record

ArticleMembranes2023

Preparation of a Low-Protein-Fouling and High-Protein-Retention Membrane via Novel Pre-Hydrolysis Treatment of Polyacrylonitrile (PAN).

Dong Xu, Guangyao Pan, Yutong Ge, Xuan Yang

Abstract read
In one paragraph

Article in Membranes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dong XuNational University of Singapore (Suzhou) Research Institute, Suzhou 215123, China.
Guangyao PanNational University of Singapore (Suzhou) Research Institute, Suzhou 215123, China.
Yutong GeNational University of Singapore (Suzhou) Research Institute, Suzhou 215123, China.
Xuan YangNational University of Singapore (Suzhou) Research Institute, Suzhou 215123, China.ORCID 0000-0002-0666-6941

Funding

Environmental and Energy Nanotechnology Innovation Platform, National University of Singapore (Suzhou) Research Institute YZCXPT2022205Science and Technology Project of Jiangsu Province BZ2022056
6 · The paper itself

Abstract

The attainment of high-protein-retention and low-protein-fouling membranes is crucial for industries that necessitate protein production or separation process. The present study aimed to develop a novel method for preparing polyacrylonitrile (PAN) membranes possessing a highly hydrophilic and negatively charged surface as well as interior structure. The method involved a pre-hydrolysis treatment during the preparation of the PAN dope solution, followed by phase inversion in an alkaline solution. Chemical and material characterization of the dopes and membranes uncovered that the cyclized PAN structure served as a reaction intermediate that facilitated strong hydrolysis effect during phase inversion and homogeneously formed carboxyl groups in the membrane's interior structure. The resulting membrane showed a highly hydrophilic surface with a contact angle of 12.4° and demonstrated less than 21% flux decay and more than 95% flux recovery during multi-cycle filtration of bovine serum albumin (BSA) solution, with a high protein rejection rate of 96%. This study offers a facile and effective alternative for preparing PAN membranes with enhanced antifouling and protein-retention properties.

Indexed as

anti-fouling modificationhigh protein retentionhydrolysis treatmentmembrane preparationpolyacrylonitrile

Identifiers

PMID36984698
PMCPMC10051198

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.