Evidence map›Paper›PMID 36984460›Full record

ArticleMedicina (Kaunas, Lithuania)2023

The Use of Liquid Biopsy in the Molecular Analysis of Plasma Compared to the Tumour Tissue from a Patient with Brain Metastasis: A Case Report.

Veronica Aran, Vinicius Mansur Zogbi, Renan Lyra Miranda, Felipe Andreiuolo, Nathalie Henriques Silva Canedo, Carolina Victor Nazaré, Paulo Niemeyer Filho, Vivaldo Moura Neto

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Veronica AranLaboratório de Biomedicina do Cérebro, Instituto Estadual do Cérebro Paulo Niemeyer, Rua do Rezende156-Centro, Rio de Janeiro 20231-092, Brazil.ORCID 0000-0003-2751-0986
Vinicius Mansur ZogbiNeurosurgery Division, Instituto Estadual do Cérebro Paulo Niemeyer, Rua do Rezende156-Centro, Rio de Janeiro 20231-092, Brazil.
Renan Lyra MirandaNeuropathology and Molecular Genetics Laboratory, Instituto Estadual Do Cérebro Paulo Niemeyer, Rua do Rezende156-Centro, Rio de Janeiro 20231-092, Brazil.
Felipe AndreiuoloNeuropathology and Molecular Genetics Laboratory, Instituto Estadual Do Cérebro Paulo Niemeyer, Rua do Rezende156-Centro, Rio de Janeiro 20231-092, Brazil.ORCID 0000-0002-2568-6155
Nathalie Henriques Silva CanedoNeuropathology and Molecular Genetics Laboratory, Instituto Estadual Do Cérebro Paulo Niemeyer, Rua do Rezende156-Centro, Rio de Janeiro 20231-092, Brazil.
Carolina Victor NazaréNeurosurgery Division, Instituto Estadual do Cérebro Paulo Niemeyer, Rua do Rezende156-Centro, Rio de Janeiro 20231-092, Brazil.
Paulo Niemeyer FilhoNeurosurgery Division, Instituto Estadual do Cérebro Paulo Niemeyer, Rua do Rezende156-Centro, Rio de Janeiro 20231-092, Brazil.
Vivaldo Moura NetoLaboratório de Biomedicina do Cérebro, Instituto Estadual do Cérebro Paulo Niemeyer, Rua do Rezende156-Centro, Rio de Janeiro 20231-092, Brazil.ORCID 0000-0002-6266-043X
Instituto Estadual do Cérebro Paulo Niemeyer · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Different cancers have multiple genetic mutations, which vary depending on the affected tumour tissue. Small biopsies may not always represent all the genetic landscape of the tumour. To improve the chances of identifying mutations at different disease stages (early, during the disease course, and refractory stage), liquid biopsies offer an advantage to traditional tissue biopsy. In addition, it is possible to detect mutations related to metastatic events depending on the cancer types analysed as will be discussed in this case report, which describes a patient with brain metastasis and lung cancer that harboured

Indexed as

Brain NeoplasmsLung NeoplasmsBiomarkers, TumorBiopsyHumansLiquid BiopsyMutationBiomarkers, Tumorbrain metastasesddPCRK-RASliquid biopsylung hepatoid adenocarcinoma

Identifiers

PMID36984460
PMCPMC10055748
OpenAlexW4322500526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.