Evidence map›Paper›PMID 36983986›Full record

ArticleLife (Basel, Switzerland)2023

Understanding the Diurnal Oscillation of the Gut Microbiota Using Microbial Culture.

Guilherme Amando, André Tonon, Débora Constantino, Maria Paz Hidalgo, Pabulo Henrique Rampelotto, Francisco Montagner

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Naked-Eye and On-Site Detection ofFoods (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Trends in Microbiology 2024.Life (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Guilherme AmandoChronobiology and Sleep Laboratory, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre 90410-000, Brazil.
André TononChronobiology and Sleep Laboratory, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre 90410-000, Brazil.
Débora ConstantinoFaculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK.
Maria Paz HidalgoChronobiology and Sleep Laboratory, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre 90410-000, Brazil.ORCID 0000-0002-7886-770X
Pabulo Henrique RampelottoGraduate Program in Pharmacology and Therapeutics, Institute of Health Sciences, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre 90410-000, Brazil.ORCID 0000-0002-8992-9697
Francisco MontagnerGraduate Program in Psychiatry and Behavioral Sciences, Faculty of Medical Sciences, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre 90410-000, Brazil.
Universidade Federal do Rio Grande do Sul · BRUniversity of Surrey · GB

Funding

Hospital de Clínicas de Porto Alegre 2019-0413
6 · The paper itself

Abstract

The composition of the gut microbiota oscillates according to the light-dark cycle. However, the existing literature demonstrates these oscillations only by molecular methods. Microbial cultures are an interesting method for studying metabolically active microorganisms. In this work, we aimed to understand the diurnal oscillation of the intestinal microbiota in Wistar male rats through microbial culture analysis. Over a 24 h period, three animals were euthanized every 6 h. Intestinal segments were dissected immediately after euthanasia and diluted in phosphate-buffered saline (PBS) for plating in different culture media. The CFU/mL counts in feces samples cultured in the Brucella medium were significantly higher at ZT0, followed by ZT6, ZT18, and ZT12 (

Indexed as

anaerobic bacteriacircadian rhythmfungilight–dark cyclemicrobiology

Identifiers

PMID36983986
PMCPMC10054680
OpenAlexW4327950565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.