Evidence map›Paper›PMID 36983982›Full record

ReviewLife (Basel, Switzerland)2023

An Overview of E-Cigarette Impact on Reproductive Health.

Debbie Montjean, Marie-Hélène Godin Pagé, Marie-Claire Bélanger, Moncef Benkhalifa, Pierre Miron

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Sharing Antivaping Social Media Messages.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Trial
  3. Article
  4. Human Primary Mesenchymal Stem Cells Fail to Recover Full Osteogenic Differentiation Potential Following Washout of Electronic Cigarette Aerosol Extracts.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
  5. Review
  6. Implantation Failure: Where to Look Up?Journal of clinical medicine · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Adverse Effects of Nicotine on Human Sperm Nuclear Proteins.The world journal of men's health · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Modulation ofAmerican journal of men's health
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Debbie MontjeanFertilys Fertility Center, 1950 Maurice-Gauvin Street, Laval, QC H7S 1Z5, Canada.
Marie-Hélène Godin PagéFertilys Fertility Center, 1950 Maurice-Gauvin Street, Laval, QC H7S 1Z5, Canada.
Marie-Claire BélangerFertilys Fertility Center, 1950 Maurice-Gauvin Street, Laval, QC H7S 1Z5, Canada.
Moncef BenkhalifaFertilys Fertility Center, 1950 Maurice-Gauvin Street, Laval, QC H7S 1Z5, Canada.
Pierre MironFertilys Fertility Center, 1950 Maurice-Gauvin Street, Laval, QC H7S 1Z5, Canada.ORCID 0000-0002-3509-2369
Ottawa Fertility Centre · CACentre Hospitalier Universitaire Amiens-Picardie · FRInstitut National de la Recherche Scientifique · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electronic cigarettes (e-cigarettes) are often considered a "safe substitute" for conventional cigarette cessation. The composition of the fluid is not always clearly defined and shows a large variation within brands and manufacturers. More than 80 compounds were detected in liquids and aerosols. E-cigarettes contain nicotine, and the addition of flavorings increases the toxicity of e-cigarette vapour in a significant manner. The heat generated by the e-cigarette leads to the oxidation and decomposition of its components, eventually forming harmful constituents in the inhaled vapour. The effects of these toxicants on male and female reproduction are well established in conventional cigarette smokers. Although toxins were measured at much lower levels in e-cigarette aerosols compared to smoke from a conventional cigarette, there are concerns about their potential impact on male and female reproduction. The information available was mainly obtained from studies conducted in animal models, and investigations in humans are scarce. However, the effects observed in animal models suggest that caution should be taken when vaping and that more research needs to be conducted to identify its potential adverse effects on fertility. The prevalence of e-cigarette usage is alarming, and warnings should be made about the impact of vaping on reproductive health. This document reviews the data regarding the impact of e-cigarette use on male and female reproduction.

Indexed as

e-cigaretteinfertilityoocytereproductive healthsafetysperm

Identifiers

PMID36983982
PMCPMC10053939
OpenAlexW4327948909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.