Evidence map›Paper›PMID 36983965›Full record

ArticleLife (Basel, Switzerland)2023

Laser Therapy Changes the Expression of Matrix Metalloproteinases in Bleomycin-Induced Skin Fibrosis.

Anna G Soboleva, Vladimir V Sobolev, Mari M Karapetyan, Alexandre Mezentsev, Olga I Rud'ko, Evgenia D Davydova, Julia A Mogulevtseva, Olga V Zhukova, Irina M Korsunskaya

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Anna G SobolevaCenter for Theoretical Problems in Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednaya Kalitnikovskaya Street, 109029 Moscow, Russia.ORCID 0000-0002-9158-1933
Vladimir V SobolevCenter for Theoretical Problems in Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednaya Kalitnikovskaya Street, 109029 Moscow, Russia.ORCID 0000-0003-4779-156X
Mari M KarapetyanLLC «Smile Zone», 41 Kolpakova Street, 141008 Mytishchi, Russia.ORCID 0000-0002-4862-2779
Alexandre MezentsevCenter for Theoretical Problems in Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednaya Kalitnikovskaya Street, 109029 Moscow, Russia.
Olga I Rud'koFaculty of Biology, M.V. Lomonosov Moscow State University, 1-12 Leninskie Gory, 119991 Moscow, Russia.ORCID 0000-0001-9484-3014
Evgenia D DavydovaLLC «Smile Zone», 41 Kolpakova Street, 141008 Mytishchi, Russia.
Julia A MogulevtsevaDepartment of Agronomy and Biotechnology, Russian Agrarian University (Moscow Timiryazev Agricultural Academy), 49 Timiryazeva Street, 127550 Moscow, Russia.
Olga V ZhukovaMoscow Center of Dermatology and Cosmetology, 17 Leninsky Avenue, 119071 Moscow, Russia.
Irina M KorsunskayaCenter for Theoretical Problems in Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednaya Kalitnikovskaya Street, 109029 Moscow, Russia.
Center for Theoretical Problems of Physicochemical Pharmacology · RULomonosov Moscow State University · RURussian State Agrarian University - Moscow Timiryazev Agricultural Academy · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matrix metalloproteinases (MMPs) are often considered biomarkers of skin fibrosis. At the early stages of the pathological process, an elevation of their enzymatic activity causes significant changes in the composition of the extracellular matrix. MMPs secreted by immune cells facilitate their migration to the site of damage. Then, the immune cells eliminate the affected cells and biomolecules. Moreover, bidirectional changes in the activity of proteolytic enzymes, including MMPs, accompany wound healing. This study aimed to assess changes in the expression of

Indexed as

animal modelsbleomycin-induced skin fibrosiscutaneous fibrosisimmune responseinflammationmatrix metalloproteinasesscarsskin damageskin remodelingwound healing

Identifiers

PMID36983965
PMCPMC10056988
OpenAlexW4327715698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.