Evidence map›Paper›PMID 36983963›Full record

ArticleLife (Basel, Switzerland)2023

Vitamin D

Eva Dědečková, Roman Viták, Michal Jirásko, Markéta Králová, Ondřej Topolčan, Ladislav Pecen, Tomáš Fürst, Pavel Brož, Radek Kučera

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Effect of 12-Week BMI-Based Vitamin DInternational journal of molecular sciences · 2023
    Trial
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Eva DědečkováDepartment of Pharmacology and Toxicology, Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.
Roman VitákDepartment of Pharmacology and Toxicology, Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.ORCID 0009-0009-2895-2541
Michal JiráskoDepartment of Pharmacology and Toxicology, Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.ORCID 0000-0002-4874-7723
Markéta KrálováDepartment of Pharmacology and Toxicology, Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.
Ondřej TopolčanDepartment of Immunochemistry, University Hospital and Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.
Ladislav PecenDepartment of Immunochemistry, University Hospital and Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.
Tomáš FürstFaculty of Science, Palacky University in Olomouc, 779 00 Olomouc, Czech Republic.
Pavel BrožDepartment of Clinical Biochemistry and Hematology, University Hospital and Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.
Radek KučeraDepartment of Pharmacology and Toxicology, Faculty of Medicine in Pilsen, Charles University, 323 00 Pilsen, Czech Republic.ORCID 0000-0002-2739-2302
Charles University · CZPalacký University Olomouc · CZ

Funding

This study was supported by Ministry of Health, Czech Republic - conceptual development of research organization (Faculty Hospital in Pilsen - FNPl, 00669806), BBMRI-CZ: Biobank net-work - a versatile platform for the research of the etiopathogenesis of d 00669806
6 · The paper itself

Abstract

backgroundScientific studies point to a significant global vitamin D deficiency. The recommended dose of vitamin D for the adult population in Central Europe is 800-2000 IU/day. The aim of our study was to determine whether doses of 1000 IU or 2000 IU of vitamin D

methodsSeventy-two healthy volunteers, average age twenty-two, took part in the study. The study was conducted from October to March in order to eliminate intra-dermal vitamin D production. Vitamin D

resultsThe dose of 1000 IU, taken for 60 days, increased vitamin D levels relatively little. Furthermore, serum vitamin D levels decreased in the 30 days following the cessation of supplementation. Taking 2000 IU daily led to a sharp increase in serum levels which plateaued 30 days after the subjects stopped using vitamin D

conclusionsBoth doses, taken daily, can help maintain adequate vitamin D levels during the winter months. A daily dose of 2000 IU, however, maintained the desired levels of vitamin D for a longer period.

Indexed as

serum levelsupplementationvitamin Dvitamin D deficiencyvitamin D insufficiency

Identifiers

PMID36983963
PMCPMC10053989
OpenAlexW4327621583

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.