Evidence map›Paper›PMID 36983936›Full record

ArticleLife (Basel, Switzerland)2023

Severe Course of COVID-19 and Long-COVID-19 in Children: Difficulties in Diagnosis.

Elena Vasichkina, Olga Kofeynikova, Svetlana Fetisova, Anastasia Y Starshinova, Elizaveta Sheyanova, Tatiana Vershinina, Anton Ryzhkov, Aleksey Skripnik, Daria Alekseeva, Elizaveta Nechaeva and 4 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Elena VasichkinaAlmazov National Medical Research Centre, St. Petersburg 197341, Russia.ORCID 0000-0001-7336-4102
Olga KofeynikovaAlmazov National Medical Research Centre, St. Petersburg 197341, Russia.
Svetlana FetisovaAlmazov National Medical Research Centre, St. Petersburg 197341, Russia.
Anastasia Y StarshinovaMedical Department, Saint Petersburg State Pediatric Medical University, St. Petersburg 194100, Russia.
Elizaveta SheyanovaAlmazov National Medical Research Centre, St. Petersburg 197341, Russia.
Tatiana VershininaAlmazov National Medical Research Centre, St. Petersburg 197341, Russia.
Anton RyzhkovAlmazov National Medical Research Centre, St. Petersburg 197341, Russia.
Aleksey SkripnikAlmazov National Medical Research Centre, St. Petersburg 197341, Russia.
Daria AlekseevaAlmazov National Medical Research Centre, St. Petersburg 197341, Russia.ORCID 0000-0003-1751-1424
Elizaveta NechaevaAlmazov National Medical Research Centre, St. Petersburg 197341, Russia.
Anzhela GlushkovaV.M. Bekhterev National Research Medical Center for Psychiatry and Neurology, St. Petersburg 192019, Russia.
Dmitry KudlayPharmacology Department, I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Moscow 119435, Russia.ORCID 0000-0003-1878-4467
Tatiana PervuninaAlmazov National Medical Research Centre, St. Petersburg 197341, Russia.
Anna StarshinovaAlmazov National Medical Research Centre, St. Petersburg 197341, Russia.
Federal Almazov North-West Medical Research Centre · RUSechenov University · RUSt.Petersburg V.M.Bekhterev Psychoneurological Research Institute · RU

Funding

Federal Almazov North-West Medical Research Centre 075-15-2022-301
6 · The paper itself

Abstract

The question of COVID-19 and long-COVID-19 course in children remains unsolved. This infection in children, which is associated with COVID-19, can vary from asymptomatic to systemic damage of various systems. Multisystem inflammatory syndrome in children, associated with SARS-CoV-2 (MIS-C), is a serious condition in children and adolescents after experiencing COVID-19. Published data on MIS-C have indicated that the inflammation can be registered in the gastrointestinal tract (60-100%), as well as in cardiovascular (80%), nervous (29-58%), and respiratory (21-65%) systems. However, with the changing characteristics of SARS-CoV-2, the manifestations of COVID-19 and long-COVID-19 in children have also been changing. Currently, there is no clear understanding of the development of severe COVID-19 and MIS-C in children, especially after being exposed to patients with COVID-19. We presented two new clinical courses of multisystem inflammatory syndrome in children with severe multisystem damage after close contact to relatives with COVID-19 or long-COVID-19. Thus, high-risk children, who are positive for SARS-CoV-2 infection after contact with COVID-19 patients, should be clinically managed during the first few months. The identification of the disease complexity requires the involvement of neurologists, cardiologists, and other specialists.

Indexed as

cardiovascular inflammationchildrencoronavirus infectionCOVID-19long-COVID-19multisystem inflammatory syndrome in childrenSARS-CoV-2

Identifiers

PMID36983936
PMCPMC10056761
OpenAlexW4324143761

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.