Evidence map›Paper›PMID 36983848›Full record

ArticleLife (Basel, Switzerland)2023

Is Erythrocyte Sedimentation Rate Necessary for the Initial Diagnosis of Giant Cell Arteritis?

Michael S Hansen, Oliver N Klefter, Lene Terslev, Mads R Jensen, Jane M Brittain, Uffe M Døhn, Carsten Faber, Steffen Heegaard, Anne K Wiencke, Yousif Subhi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Michael S HansenDepartment of Ophthalmology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark.ORCID 0000-0001-8610-7455
Oliver N KlefterDepartment of Ophthalmology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark.ORCID 0000-0003-2313-5648
Lene TerslevCenter for Rheumatology and Spine Diseases, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark.
Mads R JensenDepartment of Clinical Physiology and Nuclear Medicine, Bispebjerg & Frederiksberg Hospital, DK-2400 Copenhagen, Denmark.
Jane M BrittainDepartment of Clinical Physiology and Nuclear Medicine, Rigshospitalet, DK-2100 Copenhagen, Denmark.
Uffe M DøhnCenter for Rheumatology and Spine Diseases, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark.
Carsten FaberDepartment of Ophthalmology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark.ORCID 0000-0002-2517-7270
Steffen HeegaardDepartment of Ophthalmology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark.
Anne K WienckeDepartment of Ophthalmology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark.ORCID 0009-0002-5996-7841
Yousif SubhiDepartment of Ophthalmology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark.ORCID 0000-0001-6620-5365
Steffen HamannDepartment of Ophthalmology, Rigshospitalet, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark.ORCID 0000-0003-4318-2716
University of Copenhagen · DKFrederiksberg Hospital · DKRigshospitalet · DK

Funding

Synoptik Foundation and the Danish Rheumatism Association N/A
6 · The paper itself

Abstract

Giant cell arteritis (GCA) is an ophthalmological emergency that can be difficult to diagnose and prompt treatment is vital. We investigated the sequential diagnostic value for patients with suspected GCA using three biochemical measures as they arrive to the clinician: first, platelet count, then C-reactive protein (CRP), and lastly, erythrocyte sedimentation rate (ESR). This retrospective cross-sectional study of consecutive patients with suspected GCA investigated platelet count, CRP, and ESR using diagnostic test accuracy statistics and odds ratios (ORs) in a sequential fashion. The diagnosis was established by experts at follow-up, considering clinical findings and tests including temporal artery biopsy. A total of 94 patients were included, of which 37 (40%) were diagnosed with GCA. Compared with those without GCA, patients with GCA had a higher platelet count (

Indexed as

biomarkersC-reactive proteindiagnostic test accuracyerythrocyte sedimentation rategiant cell arteritisplatelet countsequential biomarker analysis

Identifiers

PMID36983848
PMCPMC10058337
OpenAlexW4323319072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.