Evidence map›Paper›PMID 36983774›Full record

ReviewLife (Basel, Switzerland)2023

Maternal Exposure to Cigarette Smoke during Pregnancy and Testicular Cancer in Offspring: A Systematic Review and Meta-Analysis.

Astrid L Beck, Elvira V Bräuner, Russ Hauser, Youn-Hee Lim, Cecilie S Uldbjerg, Anders Juul

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Astrid L BeckDepartment of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0003-3366-9723
Elvira V BräunerDepartment of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0001-9183-4796
Russ HauserHarvard T.H. Chan School of Public Health, Harvard University, Cambridge, MA 02138, USA.
Youn-Hee LimSection of Environmental Health, Department of Public Health, University of Copenhagen, 1014 Copenhagen, Denmark.
Cecilie S UldbjergDepartment of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0002-4041-094X
Anders JuulDepartment of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0002-0534-4350
Copenhagen University Hospital · DKUniversity of Copenhagen · DKHarvard University · US

Funding

Prenatal Exposure to Endocrine Disrupting Chemicals and Risk of Testicular Cancer (DISRUPT)R01CA236816 · NCI · REGION HOVEDSTADEN · PI JUUL, ANDERS · 2020 to 2022
$863k
Helsefonden 18-B-0016NCI NIH HHS R01 CA236816NIH HHS 1R01CA236816-01A1
6 · The paper itself

Abstract

backgroundMaternal exposure to cigarette smoke in pregnancy may play a role in the development of testicular cancer in offspring. An updated and comprehensive systematic review of the available evidence is needed.

objectiveTo identify and evaluate current evidence on maternal exposure to cigarette smoke during pregnancy and testicular cancer in offspring.

methodsA systematic search of English peer-reviewed original literature in PubMed through a block search approach. Publications were considered if assessing maternal exposure to cigarette smoke and the risk of testicular cancer in offspring.

resultsAmong the 636 identified records, 14 publications were eligible for review and 10 for meta-analysis. Quality assessment of the publications was conducted. Most included publications were case-control studies (

conclusionsThis systematic review did not provide evidence of an association between maternal exposure to cigarette smoke and risk of testicular cancer in offspring. An overall positive trend was suggested, but it had low statistical precision. The methodological limitations across publications encourage further research based on valid exposure data.

Indexed as

cigarette smokeepidemiologymeta-analysisprenatal exposuresystematic reviewtesticular cancer

Identifiers

PMID36983774
PMCPMC10054792
OpenAlexW4321597092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.