Evidence map›Paper›PMID 36983701›Full record

ArticleJournal of personalized medicine2023

Automatic Diagnosis of Infectious Keratitis Based on Slit Lamp Images Analysis.

Shaodan Hu, Yiming Sun, Jinhao Li, Peifang Xu, Mingyu Xu, Yifan Zhou, Yaqi Wang, Shuai Wang, Juan Ye

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  8. Review
  9. Review
  10. Emerging diagnostic modalities in microbial keratitis: Beyond culture and smear.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Shaodan HuDepartment of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, China.ORCID 0000-0003-1177-0679
Yiming SunDepartment of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, China.
Jinhao LiSchool of Mechanical, Electrical and Information Engineering, Shandong University, Weihai 264209, China.ORCID 0000-0002-9967-4675
Peifang XuDepartment of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, China.
Mingyu XuDepartment of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, China.
Yifan ZhouDepartment of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, China.
Yaqi WangCollege of Media Engineering, Communication University of Zhejiang, Hangzhou 310018, China.ORCID 0000-0002-4627-3392
Shuai WangSchool of Mechanical, Electrical and Information Engineering, Shandong University, Weihai 264209, China.
Juan YeDepartment of Ophthalmology, College of Medicine, The Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, China.
Second Affiliated Hospital of Zhejiang University · CNShandong University · CNCommunication University of Zhejiang · CN

Funding

Clinical Medical Research Center for Eye Diseases of Zhejiang Province 2021E50007National Natural Science Foundation of China 81870635National Natural Science Foundation Regional Innovation and Development Joint Fund U20A20386Natural Science Foundation of Shandong Provincial 2022HWYQ-041
6 · The paper itself

Abstract

Infectious keratitis (IK) is a common ophthalmic emergency that requires prompt and accurate treatment. This study aimed to propose a deep learning (DL) system based on slit lamp images to automatically screen and diagnose infectious keratitis. This study established a dataset of 2757 slit lamp images from 744 patients, including normal cornea, viral keratitis (VK), fungal keratitis (FK), and bacterial keratitis (BK). Six different DL algorithms were developed and evaluated for the classification of infectious keratitis. Among all the models, the EffecientNetV2-M showed the best classification ability, with an accuracy of 0.735, a recall of 0.680, and a specificity of 0.904, which was also superior to two ophthalmologists. The area under the receiver operating characteristics curve (AUC) of the EffecientNetV2-M was 0.85; correspondingly, 1.00 for normal cornea, 0.87 for VK, 0.87 for FK, and 0.64 for BK. The findings suggested that the proposed DL system could perform well in the classification of normal corneas and different types of infectious keratitis, based on slit lamp images. This study proves the potential of the DL model to help ophthalmologists to identify infectious keratitis and improve the accuracy and efficiency of diagnosis.

Indexed as

automatic classificationdeep learninginfectious keratitisslit lamp image

Identifiers

PMID36983701
PMCPMC10056612
OpenAlexW4324149694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.