Evidence map›Paper›PMID 36983385›Full record

ArticleJournal of clinical medicine2023

Impact of Lumbar Surgery on Pharmacological Treatment for Patients with Lumbar Spinal Canal Stenosis: A Single-Center Retrospective Study.

Takaya Imai, Sota Nagai, Takehiro Michikawa, Risa Inagaki, Soya Kawabata, Kaori Ito, Kurenai Hachiya, Hiroki Takeda, Daiki Ikeda, Shigeki Yamada and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Takaya ImaiDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, Toyoake 470-1192, Japan.
Sota NagaiDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, Toyoake 470-1192, Japan.
Takehiro MichikawaDepartment of Environmental and Occupational Health, School of Medicine, Toho University, Tokyo 143-8541, Japan.ORCID 0000-0002-2298-5133
Risa InagakiDepartment of Clinical Pharmacy, School of Medicine, Fujita Health University, Toyoake 470-1192, Japan.
Soya KawabataDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, Toyoake 470-1192, Japan.
Kaori ItoDepartment of Clinical Pharmacy, School of Medicine, Fujita Health University, Toyoake 470-1192, Japan.
Kurenai HachiyaDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, Toyoake 470-1192, Japan.
Hiroki TakedaDepartment of Spine and Spinal Cord Surgery, Fujita Health University, Toyoake 470-1192, Japan.
Daiki IkedaDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, Toyoake 470-1192, Japan.
Shigeki YamadaDepartment of Clinical Pharmacy, School of Medicine, Fujita Health University, Toyoake 470-1192, Japan.
Nobuyuki FujitaDepartment of Orthopaedic Surgery, School of Medicine, Fujita Health University, Toyoake 470-1192, Japan.
Shinjiro KanekoDepartment of Spine and Spinal Cord Surgery, Fujita Health University, Toyoake 470-1192, Japan.
Fujita Health University · JPToho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment for lumbar spinal canal stenosis (LSCS) is mainly classified into conservative and surgical therapies. Among conservative therapies, pharmacological treatment is commonly prescribed for LSCS. Meanwhile, surgical treatment is the last option for LSCS. This study aimed to examine the impact of lumbar surgery on pharmacological treatment for patients with LSCS. Consecutive patients aged ≥ 40 years who underwent lumbar surgery for LSCS were identified. A total of 142 patients were retrospectively reviewed for preoperative and 6-month and 1-year postoperative LSCS medications. The results showed that the number of LSCS medications significantly decreased after lumbar surgery. The proportion of the patients taking non-steroidal anti-inflammatory drugs, pregabalin/mirogabalin, opioids, prostaglandin E1 analogs, and neurotropin was significantly decreased after lumbar surgery, but that of the patients taking mecobalamin, acetaminophen, and serotonin-noradrenalin reuptake inhibitors was not significantly changed. Additionally, around 15% of the participants showed an increase in LSCS medications even after lumbar surgery. Multivariable analysis revealed that individuals without improvements in walking ability (RR: 2.7, 95% CI: 1.3-5.9) or social life (RR: 2.3, 95% CI: 1.1-5.0) had a greater risk of a postoperative increase in LSCS medications. The study results may provide physicians with beneficial information on treatment for LSCS.

Indexed as

Japanese Orthopaedic Association Back Pain Evaluation Questionnairelumbar spinal canal stenosislumbar surgerypharmacological treatmentRoland-Morris Disability Questionnairesocial lifesurgical effectivenesswalking abilityZurich Claudication Questionnaire

Identifiers

PMID36983385
PMCPMC10056014
OpenAlexW4327953223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.