ReviewJournal of clinical medicine2023
Endometrial Cytology in Diagnosis of Endometrial Cancer: A Systematic Review and Meta-Analysis of Diagnostic Accuracy.
Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Integrating epigenetic and metabolic indicators for non-invasive endometrial cancer triage: a machine learning approach.BMC women's health · 2026Article
- Lactate transmission from hypoxic tumor cells promotes macrophage senescence and M2 polarization via the DNMT1-NHE7 axis to accelerate endometrial cancer progression.Cell death & disease · 2026Article
- Validation of a cervical CDO1/CELF4 methylation test for endometrial cancer: a prospective paired-sample comparison with intrauterine specimen.Frontiers in medicine · 2026Article
- Intratumoral and peritumoral MRI habitat imaging for differentiating stage IA endometrial cancer from benign endometrial lesions: a multicenter study.Frontiers in oncology · 2026Article
- An integrated system from microscopy to AI for real-time object detection in endometrial cytology.Journal of pathology informatics · 2026Article
- Evaluation of Diagnostic Accuracy of Directly Sampled Endometrial Cytology Using ThinPrep for Endometrial Malignancies: Comparison With Existing Endometrial Liquid-Based Cytology.Cytopathology : official journal of the British Society for Clinical Cytology · 2025Article
- Screening and Early Diagnosis in Gynecological Cancers.Cancers · 2023Article
- Article
- Clinical study of classification and regression tree assisted endometrial biopsy in the diagnosis of endometrial carcinoma.American journal of cancer research · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBecause the incidence of endometrial cancer has been increasing every year, it is important to identify an effective screening method for it. The endometrial cytology test (ECT) is considered to be the more acceptable technique compared to invasive endometrial sampling.
methodsThe study followed the Priority Reporting Project for Systematic Evaluation and Meta-Analysis (PRISMA-DTA) protocol. This systematic rating searched EMBASE and Web of Science databases for studies on ECT for endometrial cancer from the databases' dates of inception to 30 September 2022. All literature screening and data extraction were performed by two researchers, while the methodological quality of the included studies was assessed against defined inclusion criteria. And a third researcher resolves the disagreements.
resultsTwenty-six studies were eventually included in this final analysis. Meta-analysis results showed that the diagnostic accuracy characteristics of ECT for endometrial cancer were as follows: combined sensitivity = 0.84 [95% confidence interval (CI) (0.83-0.86)], combined specificity = 0.98 [95% CI (0.98-0.98)], combined positive likelihood ratio = 34.65 [95% CI (20.90-57.45)], combined negative likelihood ratio = 0.21 [95% CI (0.15-0.30)], and area under the summary receiver operating characteristic curve = 0.9673.
conclusionsECT had the ability to detect endometrial cancer with strong specificity, although some studies have demonstrated significant differences in sensitivity.
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