ReviewJournal of clinical medicine2023
Cerebral Protection Strategies and Stroke in Surgery for Acute Type A Aortic Dissection.
Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Retrospective Cohort Study Evaluating the Efficacy of Bilateral Modified Catheter Antegrade Cerebral Perfusion (Modified bACP) in Acute Type A Aortic Dissection Surgery
A Retrospective Chart-Review Evaluating Direct Three-Vessel Antegrade Cerebral Perfusion Versus Unilateral Right Axillary Antegrade Cerebral Perfusion in Emergency Total Arch Replacement for Acute Type A Aortic Dissection at CMUH (2021-2025)
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Surgical strategies in elderly patients with acute type A aortic dissection-a systematic review.Frontiers in surgery · 2026Pooled it
- Adjusted comparison of antegrade cerebral perfusion techniques during prolonged circulatory arrest in surgery for acute type A aortic dissection.JTCVS open · 2026Article
- Safety and efficacy of mild hypothermic circulatory arrest with bilateral cerebral perfusion in acute aortic dissection surgery: a retrospective cohort study.Journal of thoracic disease · 2026Article
- Circulatory arrest time above 30 min have significantly detrimental effects on the outcomes of type a aortic dissection repair.Journal of cardiothoracic surgery · 2026Article
- Development of a scoring system for the involvement of supra-aortic vessel in patients with type A aortic dissection.Journal of thoracic disease · 2026Article
- Aortic Arch and Frozen Elephant Trunk Surgery: Anesthetic Challenges and Strategies for Organ Protection.Journal of clinical medicine · 2026Review
- Predictors and outcomes in patients undergoing surgery for acute type A aortic dissection requiring concomitant venoarterial extracorporeal membrane oxygenation support-a retrospective multicentre cohort study.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025Observational
- Effect of dexmedetomidine on postoperative delirium in patients undergoing type A aortic dissection surgery: a prospective cohort study.Journal of thoracic disease · 2025Article
- Aortic versus axillary artery cannulation for hemiarch replacement: single-centre real-world experience.BMC cardiovascular disorders · 2024Article
- Postoperative stroke in acute type A aortic dissection: incidence, outcomes, and perioperative risk factors.BMC surgery · 2024Article
- The impact of onset-to-cut time in surgery for stable acute type A aortic dissection-a single-centre retrospective cohort study.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- The Ascyrus Medical Dissection Stent: A One-Fits-All Strategy for the Treatment of Acute Type A Aortic Dissection?Journal of clinical medicine · 2024Review
- Relative band power in assessing temporary neurological dysfunction post- type A aortic dissection surgery: a prospective study.Scientific reports · 2024Observational
- Cerebral protection in acute type A aortic dissection surgery: a systematic review and meta-analysis.Journal of thoracic disease · 2024Article
- Cerebral protection strategies for type A aortic dissection repair.Indian journal of thoracic and cardiovascular surgery · 2023Review
- Aortic arch branch-prioritized reconstruction for type A aortic dissection surgery.Frontiers in cardiovascular medicine · 2023Article
- Postoperative thrombocytopenia and subsequent consequences in acute type A aortic dissection.Annals of medicine · 2023Article
- Case Report: Successful endovascular treatment of acute type A aortic dissection.Frontiers in cardiovascular medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPerioperative stroke remains a devastating complication in the operative treatment of acute type A aortic dissection. To reduce the risk of perioperative stroke, different perfusion techniques can be applied. A consensus on the preferred cerebral protection strategy does not exist.
methodsTo provide an overview about the different cerebral protection strategies, literature research on Medline/PubMed was performed. All available original articles reporting on cerebral protection in surgery for acute type A aortic dissection and neurologic outcomes since 2010 were included.
resultsAntegrade and retrograde cerebral perfusion may provide similar neurological outcomes while outperforming deep hypothermic circulatory arrest. The choice of arterial cannulation site and chosen level of hypothermia are influencing factors for perioperative stroke.
conclusionsDeep hypothermic circulatory arrest is not recommended as the sole cerebral protection technique. Antegrade and retrograde cerebral perfusion are today's standard to provide cerebral protection during aortic surgery. Bilateral antegrade cerebral perfusion potentially leads to superior outcomes during prolonged circulatory arrest times between 30 and 50 min. Arterial cannulation sites with antegrade perfusion (axillary, central or carotid artery) in combination with moderate hypothermia seem to be advantageous. Every concept should be complemented by adequate intraoperative neuromonitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.