Evidence map›Paper›PMID 36983247›Full record

ArticleJournal of clinical medicine2023

Impact of Sociodemographic, Premorbid, and Injury-Related Factors on Patient-Reported Outcome Trajectories after Traumatic Brain Injury (TBI).

Nicole von Steinbuechel, Stefanie Hahm, Holger Muehlan, Juan Carlos Arango-Lasprilla, Fabian Bockhop, Amra Covic, Silke Schmidt, Ewout W Steyerberg, Andrew I R Maas, David Menon and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Survival status, mortality predictors, and scores in patients with severe traumatic brain injury in the intensive care unit.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nicole von SteinbuechelInstitute of Medical Psychology and Medical Sociology, University Medical Center Goettingen, Waldweg 37A, 37073 Goettingen, Germany.
Stefanie HahmDepartment Health & Prevention, Institute of Psychology, University of Greifswald, Robert-Blum-Str. 13, 17489 Greifswald, Germany.
Holger MuehlanDepartment Health & Prevention, Institute of Psychology, University of Greifswald, Robert-Blum-Str. 13, 17489 Greifswald, Germany.ORCID 0000-0001-8048-5682
Juan Carlos Arango-LasprillaDepartments of Psychology and Physical Medicine and Rehabilitation, Virginia Commonwealth University, 907 Floyd Ave., Richmond, VA 23284, USA.ORCID 0000-0002-7184-8311
Fabian BockhopInstitute of Medical Psychology and Medical Sociology, University Medical Center Goettingen, Waldweg 37A, 37073 Goettingen, Germany.ORCID 0000-0001-8892-896X
Amra CovicInstitute of Medical Psychology and Medical Sociology, University Medical Center Goettingen, Waldweg 37A, 37073 Goettingen, Germany.
Silke SchmidtDepartment Health & Prevention, Institute of Psychology, University of Greifswald, Robert-Blum-Str. 13, 17489 Greifswald, Germany.
Ewout W SteyerbergDepartment of Biomedical Data Sciences, Leiden University Medical Center, 2333 RC Leiden, The Netherlands.ORCID 0000-0002-7787-0122
Andrew I R MaasDepartment of Neurosurgery, Antwerp University Hospital and University of Antwerp, 2650 Edegem, Belgium.ORCID 0000-0003-1612-1264
David MenonDivision of Anaesthesia, University of Cambridge/Addenbrooke's Hospital, Box 157, Cambridge CB2 0QQ, UK.
Nada AndelicDepartment of Physical Medicine and Rehabilitation, Oslo University Hospital, 0450 Oslo, Norway.ORCID 0000-0002-3719-4406
Marina ZeldovichInstitute of Medical Psychology and Medical Sociology, University Medical Center Goettingen, Waldweg 37A, 37073 Goettingen, Germany.ORCID 0000-0003-0172-9904
The Center-Tbi Participants And Investigators

Funding

European Union 7th Framework programme 602150Hannelore Kohl Stiftung (Germany)Integra LifeSciences Corporation (USA)NeuroTrauma Sciences (USA)OneMind (USA)
6 · The paper itself

Abstract

Traumatic brain injury (TBI) remains one of the leading causes of death and disability worldwide. To better understand its impact on various outcome domains, this study pursues the following: (1) longitudinal outcome assessments at three, six, and twelve months post-injury; (2) an evaluation of sociodemographic, premorbid, and injury-related factors, and functional recovery contributing to worsening or improving outcomes after TBI. Using patient-reported outcome measures, recuperation trends after TBI were identified by applying Multivariate Latent Class Mixed Models (MLCMM). Instruments were grouped into TBI-specific and generic health-related quality of life (HRQoL; QOLIBRI-OS, SF-12v2), and psychological and post-concussion symptoms (GAD-7, PHQ-9, PCL-5, RPQ). Multinomial logistic regressions were carried out to identify contributing factors. For both outcome sets, the four-class solution provided the best match between goodness of fit indices and meaningful clinical interpretability. Both models revealed similar trajectory classes: stable good health status (HRQoL:

Indexed as

health-related quality of life (HRQoL)long-term outcomesmental healthMultivariate Latent Class Mixed Models (MLCMM)recuperation trajectoriestraumatic brain injury

Identifiers

PMID36983247
PMCPMC10052290

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.