Evidence map›Paper›PMID 36983222›Full record

ReviewJournal of clinical medicine2023

Safety and Efficacy of Different Anticoagulant Doses for Patients with COVID-19 in the ICU: A Systematic Review and Meta-Analysis.

Svetlana Rachina, Yuliya Belkova, Anastasia Shchendrygina, Aleksandr Suvorov, Denis Bourgeois, Marina Karuk, Violetta Sitnikova, Nikita Dyatlov

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Svetlana RachinaHospital Therapy Department No. 2, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia.ORCID 0000-0002-3329-7846
Yuliya BelkovaDepartment of Clinical Pharmacology, Smolensk State Medical University, 214019 Smolensk, Russia.ORCID 0000-0002-4422-6517
Anastasia ShchendryginaHospital Therapy Department No. 2, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia.
Aleksandr SuvorovInstitute of Biodesign and Complex Systems Modeling, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia.
Denis BourgeoisHealth Systemic Process (P2S), Research Unit UR4129, University Claude Bernard Lyon 1, University of Lyon, 69008 Lyon, France.ORCID 0000-0003-4754-2512
Marina KarukEndovascular Surgery Department, Russian Research Center of Surgery Named after Academician B.V. Petrovsky, 119991 Moscow, Russia.ORCID 0000-0002-2292-6758
Violetta SitnikovaHospital Therapy Department No. 2, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia.
Nikita DyatlovHospital Therapy Department No. 2, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia.
Sechenov University · RURussian Scientific Center of Surgery · RUSmolensk State Medical University · RUUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Critically ill COVID-19 patients have a high incidence of thromboembolic events, which significantly influence the risk of mortality. Anticoagulant therapy is generally recommended to these patients but the optimal dosing regimens require further investigations. The objective of this systematic review and meta-analysis was to assess the efficacy and safety of prophylactic, intermediate and therapeutic dose anticoagulation in COVID-19 patients admitted to the ICU. A systematic search for original prospective observational studies and clinical trials was performed in online databases from 2020 to 2022. A total of 13 studies (3239 patients) were included. The type of anticoagulant dosing showed no significant influence on short-term mortality (

Indexed as

anticoagulantCOVID-19deep vein thrombosisheparinICUpulmonary embolismthromboprophylaxisvenous thromboembolism

Identifiers

PMID36983222
PMCPMC10057479
OpenAlexW4324149690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.