Evidence map›Paper›PMID 36983124›Full record

ArticleJournal of clinical medicine2023

Long-Term Adverse Effects of Mild COVID-19 Disease on Arterial Stiffness, and Systemic and Central Hemodynamics: A Pre-Post Study.

Mario Podrug, Pjero Koren, Edita Dražić Maras, Josip Podrug, Viktor Čulić, Maria Perissiou, Rosa Maria Bruno, Ivana Mudnić, Mladen Boban, Ana Jerončić

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Observational
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  4. Observational
  5. Review
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  9. Observational
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mario PodrugLaboratory of Vascular Aging, University of Split School of Medicine, 21000 Split, Croatia.
Pjero KorenLaboratory of Vascular Aging, University of Split School of Medicine, 21000 Split, Croatia.
Edita Dražić MarasInfectious Diseases Department, University Hospital of Split, 21000 Split, Croatia.
Josip PodrugOtorhinolaryngology Department, University Hospital of Split, 21000 Split, Croatia.
Viktor ČulićUniversity of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0002-4026-0195
Maria PerissiouPhysical Activity, Health and Rehabilitation Research Group, School of Sport, Health and Exercise Science, Faculty of Science and Health, University of Portsmouth, Portsmouth PO1 2UP, UK.ORCID 0000-0002-3974-2250
Rosa Maria BrunoUniversité Paris Cité, INSERM, PARCC, 75015 Paris, France.
Ivana MudnićDepartment of Basic and Clinical Pharmacology, University of Split School of Medicine, 21000 Split, Croatia.
Mladen BobanDepartment of Basic and Clinical Pharmacology, University of Split School of Medicine, 21000 Split, Croatia.
Ana JerončićLaboratory of Vascular Aging, University of Split School of Medicine, 21000 Split, Croatia.ORCID 0000-0003-1621-1956

Funding

Croatian Science Foundation No. IP-2018-01-4729
6 · The paper itself

Abstract

COVID-19-associated vascular disease complications are primarily associated with endothelial dysfunction; however, the consequences of disease on vascular structure and function, particularly in the long term (>7 weeks post-infection), remain unexplored. Individual pre- and post-infection changes in arterial stiffness as well as central and systemic hemodynamic parameters were measured in patients diagnosed with mild COVID-19. As part of in-laboratory observational studies, baseline measurements were taken up to two years before, whereas the post-infection measurements were made 2-3 months after the onset of COVID-19. We used the same measurement protocol throughout the study as well as linear and mixed-effects regression models to analyze the data. Patients (N = 32) were predominantly healthy and young (mean age ± SD: 36.6 ± 12.6). We found that various parameters of arterial stiffness and central hemodynamics-cfPWV, AIx@HR75, and cDBP as well as DBP and MAP-responded to a mild COVID-19 disease. The magnitude of these responses was dependent on the time since the onset of COVID-19 as well as age (p

Indexed as

arterial stiffnessautoimmune responsecentral hemodynamicsCOVID-19long COVID-19 syndromevascular remodeling

Identifiers

PMID36983124
PMCPMC10055477

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.