Evidence map›Paper›PMID 36983092›Full record

ArticleJournal of clinical medicine2023

Intervortex Venous Anastomosis in the Macula in Central Serous Chorioretinopathy Imaged by En Face Optical Coherence Tomography.

José Ignacio Fernández-Vigo, Daniela Rego-Lorca, Francisco Javier Moreno-Morillo, Bárbara Burgos-Blasco, Alicia Valverde-Megías, Carmen Méndez-Hernández, Lorenzo López-Guajardo, Juan Donate-López

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Interventions for central serous chorioretinopathy: a network meta-analysis.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Characteristics of vortex vein in healthy eyes and fundus diseases imaged by ultra-widefield OCTA.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  6. Analysis of choroidal markers of activity in pachychoroid disease spectrum.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Observational
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

José Ignacio Fernández-VigoOphthalmology Department, Hospital Clínico San Carlos, Institute of Health Research (IdISSC), 28040 Madrid, Spain.ORCID 0000-0001-8745-3464
Daniela Rego-LorcaOphthalmology Department, Hospital Clínico San Carlos, Institute of Health Research (IdISSC), 28040 Madrid, Spain.ORCID 0000-0002-8076-0522
Francisco Javier Moreno-MorilloOphthalmology Department, Hospital Clínico San Carlos, Institute of Health Research (IdISSC), 28040 Madrid, Spain.ORCID 0000-0001-7748-0506
Bárbara Burgos-BlascoOphthalmology Department, Hospital Clínico San Carlos, Institute of Health Research (IdISSC), 28040 Madrid, Spain.ORCID 0000-0003-2178-6164
Alicia Valverde-MegíasOphthalmology Department, Hospital Clínico San Carlos, Institute of Health Research (IdISSC), 28040 Madrid, Spain.ORCID 0000-0002-6166-114X
Carmen Méndez-HernándezOphthalmology Department, Hospital Clínico San Carlos, Institute of Health Research (IdISSC), 28040 Madrid, Spain.ORCID 0000-0003-3413-5248
Lorenzo López-GuajardoOphthalmology Department, Hospital Clínico San Carlos, Institute of Health Research (IdISSC), 28040 Madrid, Spain.
Juan Donate-LópezOphthalmology Department, Hospital Clínico San Carlos, Institute of Health Research (IdISSC), 28040 Madrid, Spain.ORCID 0000-0002-9944-6736
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the presence of macular intervortex venous anastomosis in central serous chorioretinopathy (CSCR) patients using en face optical coherence tomography (EF-OCT).

methodsA cross-sectional study where EF-OCT 6 × 6 and 12 × 12 mm macular scans of patients with unilateral chronic CSCR were evaluated for anastomosis between vortex vein systems in the central macula. The presence of prominent anastomoses was defined as a connection with a diameter ≥150 µm between the inferotemporal and superotemporal vortex vein systems which crossed the temporal raphe. Three groups were studied: CSCR eyes (with an active disease with the presence of neurosensorial detachment; n = 135), fellow unaffected eyes (n = 135), and healthy eyes as controls (n = 110). Asymmetries, abrupt termination, sausaging, bulbosities and corkscrew appearance were also assessed.

resultsIn 79.2% of the CSCR eyes there were prominent anastomoses in the central macula between the inferotemporal and superotemporal vortex vein systems, being more frequent than in fellow eyes and controls (51.8% and 58.2% respectively). The number of anastomotic connections was higher in the affected eye group (2.9 ± 1.8) than in the unaffected fellow eye group (2.1 ± 1.7) and the controls (1.5 ± 1.6) (

conclusionsIntervortex venous anastomoses in the macula were common in CSCR, being more frequently observed in affected eyes than in fellow unaffected eyes and healthy controls. This anatomical variation could have important implications concerning the pathogenesis and classification of the disease.

Indexed as

central serous chorioretinopathychoroidal vesselsen face optical coherence tomographyintervortex veins anastomosispachychoroid disease

Identifiers

PMID36983092
PMCPMC10052017
OpenAlexW4323361341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.