Evidence map›Paper›PMID 36983054›Full record

ArticleInternational journal of molecular sciences2023

Ruthenium Complexes with Protic Ligands: Influence of the Position of OH Groups and π Expansion on Luminescence and Photocytotoxicity.

Olaitan E Oladipupo, Meredith C Prescott, Emily R Blevins, Jessica L Gray, Colin G Cameron, Fengrui Qu, Nicholas A Ward, Abigail L Pierce, Elizabeth R Collinson, James Fletcher Hall and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Olaitan E OladipupoDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL 35487, USA.ORCID 0000-0001-8677-4602
Meredith C PrescottDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL 35487, USA.
Emily R BlevinsDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL 35487, USA.
Jessica L GrayDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL 35487, USA.
Colin G CameronDepartment of Chemistry and Biochemistry, The University of Texas Arlington, Arlington, TX 76019, USA.
Fengrui QuDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL 35487, USA.
Nicholas A WardDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL 35487, USA.
Abigail L PierceDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL 35487, USA.
Elizabeth R CollinsonDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL 35487, USA.
James Fletcher HallDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL 35487, USA.
Seungjo ParkDepartment of Chemical and Biological Engineering, The University of Alabama, Tuscaloosa, AL 35487, USA.
Yonghyun KimDepartment of Chemical and Biological Engineering, The University of Alabama, Tuscaloosa, AL 35487, USA.ORCID 0000-0001-6344-1258
Sherri A McFarlandDepartment of Chemistry and Biochemistry, The University of Texas Arlington, Arlington, TX 76019, USA.
Igor FedinDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL 35487, USA.ORCID 0000-0002-3534-8336
Elizabeth T PapishDepartment of Chemistry and Biochemistry, The University of Alabama, Tuscaloosa, AL 35487, USA.

Funding

Immunomodulating Ruthenium Metal Complexes for Melanoma PhotodynamicTherapyR01CA222227 · NCI · UNIVERSITY OF TEXAS ARLINGTON · PI GUJAR, SHASHI, MCFARLAND, SHERRI · 2018 to 2022
$2.6M
Singlet oxygen formation vs. photodissociation for protic ruthenium anticancer compounds: The oxygenated substituent determines the mode of action and the cytotoxicityR15GM132803 · NIGMS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI PAPISH, ELIZABETH TABITHA · 2019 to 2022
$844k
National Science Foundation CHE 1726812, 1828078, 1919906NCI NIH HHS R01 CA222227NCI NIH HHS R01CA222227NIGMS NIH HHS R15 GM132803NIH HHS R15-GM132803
6 · The paper itself

Abstract

Protic ruthenium complexes using the dihydroxybipyridine (dhbp) ligand combined with a spectator ligand (N,N = bpy, phen, dop, Bphen) have been studied for their potential activity vs. cancer cells and their photophysical luminescent properties. These complexes vary in the extent of π expansion and the use of proximal (6,6'-dhbp) or distal (4,4'-dhbp) hydroxy groups. Eight complexes are studied herein as the acidic (OH bearing) form, [(N,N)

Indexed as

LuminescenceRutheniumLigandsLigandsRutheniumanticancerhighly conjugated ligandslight activationluminescenceprotic ligandsruthenium

Identifiers

PMID36983054
PMCPMC10053956

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.