Evidence map›Paper›PMID 36982957›Full record

ArticleInternational journal of molecular sciences2023

Theophylline-Induced Relaxation Is Enhanced after Testosterone Treatment via Increased K

Jorge Reyes-García, Verónica Díaz-Hernández, Abril Carbajal-García, María F Casas-Hernández, Bettina Sommer, Luis M Montaño

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Testosterone Enhances KInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jorge Reyes-GarcíaDepartamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0002-6226-7363
Verónica Díaz-HernándezDepartamento de Embriología y Genética, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0002-6119-3497
Abril Carbajal-GarcíaDepartamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0003-1394-9971
María F Casas-HernándezDepartamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0009-0005-8762-6798
Bettina SommerLaboratorio de Hiperreactividad Bronquial, Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Mexico City 14080, Mexico.ORCID 0000-0003-1292-9418
Luis M MontañoDepartamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico.ORCID 0000-0002-8329-4918
Universidad Nacional Autónoma de México · MXInstituto Nacional de Enfermedades Respiratorias · MX

Funding

Consejo Nacional de Ciencia y Tecnología CF/137725National Autonomous University of Mexico IN200522, IN204319, IN209520
6 · The paper itself

Abstract

Theophylline is a drug commonly used to treat asthma due to its anti-inflammatory and bronchodilatory properties. Testosterone (TES) has been suggested to reduce the severity of asthma symptoms. This condition affects boys more than girls in childhood, and this ratio reverses at puberty. We reported that guinea pig tracheal tissue chronic exposure to TES increases the expression of β

Indexed as

AsthmaTheophyllineAnimalsFemaleGuinea PigsMaleMuscle RelaxationMuscle, SmoothSexual MaturationTestosteroneTracheaTestosteroneTheophyllineairway smooth muscledelayed rectifier K+ channelstestosteronetheophylline

Identifiers

PMID36982957
PMCPMC10059212
OpenAlexW4327950569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.