Evidence map›Paper›PMID 36982894›Full record

ArticleInternational journal of molecular sciences2023

Nuclear Epidermal Growth Factor Receptor Overexpression as a Survival Predictor in Oral Squamous Cell Carcinoma.

Marko Tarle, Marina Raguž, Danko Muller, Ivica Lukšić

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. [Research progress on the mechanisms of resistance to cetuximab targeted therapy in head and neck squamous cell carcinoma].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Review
  5. Review
  6. Review
  7. Pathogenesis and Therapy of Oral Carcinogenesis.International journal of molecular sciences · 2024
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Marko TarleDepartment of Maxillofacial Surgery, Dubrava University Hospital, 10000 Zagreb, Croatia.ORCID 0000-0002-4173-1278
Marina RagužDepartment of Neurosurgery, Dubrava University Hospital, 10000 Zagreb, Croatia.
Danko MullerDepartment of Pathology and Cytology, Dubrava University Hospital, 10000 Zagreb, Croatia.
Ivica LukšićDepartment of Maxillofacial Surgery, Dubrava University Hospital, 10000 Zagreb, Croatia.ORCID 0000-0002-9138-2037
University of Zagreb · HRUniversity Hospital Dubrava · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to determine, by immunohistochemical methods, the expression of nEGFR and markers of cell proliferation (Ki-67), cell cycle (mEGFR, p53, cyclin D1), and tumor stem cells (ABCG2) in 59 pathohistological samples of healthy oral mucosa, 50 oral premalignant changes (leukoplakia and erythroplakia), and 52 oral squamous cell carcinomas (OSCC). An increase in the expression of mEGFR and nEGFR was found with the development of the disease (

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsMouth NeoplasmsCyclin D1ErbB ReceptorsHumansKi-67 AntigenLeukoplakiaSquamous Cell Carcinoma of Head and NeckTumor Suppressor Protein p53Cyclin D1ErbB ReceptorsKi-67 AntigenTumor Suppressor Protein p53biomarkersimmunocytochemistrynEGFRoral cavitysquamous cell carcinoma

Identifiers

PMID36982894
PMCPMC10056291
OpenAlexW4327967126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.