Evidence map›Paper›PMID 36982816›Full record

ReviewInternational journal of molecular sciences2023

Biotherapy Using Probiotics as Therapeutic Agents to Restore the Gut Microbiota to Relieve Gastrointestinal Tract Inflammation, IBD, IBS and Prevent Induction of Cancer.

Divakar Dahiya, Poonam Singh Nigam

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
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  6. Review
  7. Polysaccharides fromNutrients · 2025
    Review
  8. Article
  9. Review
  10. Sheep-DerivedMicroorganisms · 2025
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Sheep-derived butyrate-producingAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2024
    Article
  17. Review
  18. Review
  19. Probiotic Yeasts: A Developing Reality?Journal of fungi (Basel, Switzerland) · 2024
    Review
  20. Clinical trials of probiotics: Current outlook.Food science & nutrition · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Divakar DahiyaWexham Park Hospital, Wexham Street, Slough SL2 4HL, UK.
Poonam Singh NigamBiomedical Sciences Research Institute, Ulster University, Coleraine BT52 1SA, UK.ORCID 0000-0001-8505-5382
University of Ulster · GBWexham Park Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota is composed of several microbial strains with diverse and variable compositions in both healthy and sick people. An undisturbed gut microbiota needs to be sustained in order to perform all physiological, metabolic, and immune functions in a normal way to prevent the development of diseases. This article has reviewed the published information on the issue of disruption of the balance of the gut microbiota. This disruption could be for many reasons, such as microbial infection in the gastrointestinal tract, food poisoning, diarrhoea, chemotherapy, malnutrition, lifestyle, and ageing. If this disruption is not restored to normal, it might cause dysbiosis. Eventually, a gut microbiota interrupted by dysbiosis might initiate several health issues, such as inflammation of the gastrointestinal tract, the induction of cancer, and the progression of a variety of diseases such as irritable bowel syndrome and inflammatory bowel disease. This review concluded that biotherapy is a natural way of using probiotic products, whether in form of food, beverages, or supplements, to restore the gut microbiota disrupted by dysbiosis. Metabolites secreted by the ingested probiotics help to relieve gastrointestinal tract inflammation and can avoid the induction of cancer.

Indexed as

Gastrointestinal MicrobiomeInflammatory Bowel DiseasesIrritable Bowel SyndromeNeoplasmsProbioticsBiological TherapyDysbiosisHumansInflammationexopolysaccharidegutIBDIBSinflammationlactic acid bacteriamicrobiotaprobioticsshort-chain fatty acids

Identifiers

PMID36982816
PMCPMC10052502
OpenAlexW4327699847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.