Evidence map›Paper›PMID 36982727›Full record

ArticleInternational journal of molecular sciences2023

Se-Bin Lee, Ju-Hui Kang, Eun-Jung Sim, Ye-Rin Jung, Jeong-Hyeon Kim, Prima F Hillman, Sang-Jip Nam, Tae-Bong Kang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Role of inflammasomes in cancer immunity: mechanisms and therapeutic potential.Journal of experimental & clinical cancer research : CR · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Se-Bin LeeBK21 Project Team, Department of Applied Life Science, Graduate School, Konkuk University, Chungju 27478, Republic of Korea.
Ju-Hui KangBK21 Project Team, Department of Applied Life Science, Graduate School, Konkuk University, Chungju 27478, Republic of Korea.
Eun-Jung SimBK21 Project Team, Department of Applied Life Science, Graduate School, Konkuk University, Chungju 27478, Republic of Korea.
Ye-Rin JungBK21 Project Team, Department of Applied Life Science, Graduate School, Konkuk University, Chungju 27478, Republic of Korea.
Jeong-Hyeon KimDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul 03760, Republic of Korea.
Prima F HillmanDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul 03760, Republic of Korea.
Sang-Jip NamDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul 03760, Republic of Korea.
Tae-Bong KangBK21 Project Team, Department of Applied Life Science, Graduate School, Konkuk University, Chungju 27478, Republic of Korea.ORCID 0000-0003-1441-9470
Konkuk University · KREwha Womans University · KR

Funding

National Research Foundation of Korea 2021RIS-001
6 · The paper itself

Abstract

The AIM2 inflammasome is an innate immune system component that defends against cytosolic bacteria and DNA viruses, but its aberrant activation can lead to the progression of various inflammatory diseases, including psoriasis. However, there have been few reports of specific inhibitors of AIM2 inflammasome activation. In this study, we aimed to investigate the inhibitory activity of ethanolic extracts of seeds of

Indexed as

CornusDermatitisPsoriasisCaspase 1CaspasesDNA-Binding ProteinsHEK293 CellsHumansImiquimodInflammasomesInflammationInterleukin-1betaNLR Family, Pyrin Domain-Containing 3 ProteinPlant ExtractsSeedsAIM2 protein, humanCaspase 1CaspasesDNA-Binding ProteinsImiquimodInflammasomesInterleukin-1betaNLR Family, Pyrin Domain-Containing 3 ProteinPlant ExtractsAIM2 inflammasomeCornus officinalisIMQ-induced psoriasis-like skin inflammationmacrophage

Identifiers

PMID36982727
PMCPMC10051512
OpenAlexW4327622010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.