Evidence map›Paper›PMID 36982725›Full record

ArticleInternational journal of molecular sciences2023

Shared Genes of

Longcong Dong, Yuan Shen, Hongying Li, Ruibin Zhang, Shuguang Yu, Qiaofeng Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Monoterpene-rich essential oil fromToxicology research · 2025
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  7. Article
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  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Longcong DongAcupuncture and Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Yuan ShenAcupuncture and Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Hongying LiAcupuncture and Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Ruibin ZhangAcupuncture and Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Shuguang YuAcupuncture and Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Qiaofeng WuAcupuncture and Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Chengdu University of Traditional Chinese Medicine · CN

Funding

the Fund of Science and Technology Department of Sichuan Province, China 2021ZYD0081the Fund of Science and Technology Department of Sichuan Province, China 2022ZDZX0033the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine ZYYCXTD-D-202003the National Key R&D Program of China 2019YFC1709001the National Key R&D Program of China 2022YFC3500703the National Natural Science Foundation of China 81873383the National Natural Science Foundation of China 82174512
6 · The paper itself

Abstract

Emerging evidence shows that peripheral systemic inflammation, such as inflammatory bowel disease (IBD), has a close even interaction with central nervous disorders such as Alzheimer's disease (AD). This study is designed to further clarify the relationship between AD and ulcerative colitis (UC, a subclass of IBD). The GEO database was used to download gene expression profiles for AD (GSE5281) and UC (GSE47908). Bioinformatics analysis included GSEA, KEGG pathway, Gene Ontology (GO), WikiPathways, PPI network, and hub gene identification. After screening the shared genes, qRT-PCR, Western blot, and immunofluorescence were used to verify the reliability of the dataset and further confirm the shared genes. GSEA, KEGG, GO, and WikiPathways suggested that

Indexed as

Alzheimer DiseaseColitis, UlcerativeInflammatory Bowel DiseasesComputational BiologyHumansInflammationMacrophagesMicrogliaNitric Oxide Synthase Type IIPPAR gammaReproducibility of ResultsNitric Oxide Synthase Type IINOS2 protein, humanPPAR gammaAlzheimer’s diseasebioinformaticsNOS2PPARGshared geneulcerative colitis

Identifiers

PMID36982725
PMCPMC10058634
OpenAlexW4327600702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.