Evidence map›Paper›PMID 36982720›Full record

ArticleInternational journal of molecular sciences2023

Urinary Biomarkers in a Living Donor Kidney Transplantation Cohort-Predictive Value on Graft Function.

G J Julia Huisman, Nora A Spraakman, Jeroen V Koomen, A Marrit Talsma, Robert A Pol, Stefan P Berger, Henri G D Leuvenink, Michel M R F Struys, Gertrude J Nieuwenhuijs-Moeke

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

G J Julia HuismanUniversity Medical Center Groningen, Department of Surgery, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.ORCID 0000-0002-3081-7500
Nora A SpraakmanUniversity Medical Center Groningen, Department of Anesthesiology, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.ORCID 0000-0001-8614-589X
Jeroen V KoomenUniversity Medical Center Groningen, Department of Anesthesiology, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.ORCID 0000-0001-7253-3998
A Marrit TalsmaUniversity Medical Center Groningen, Department of Anesthesiology, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
Robert A PolUniversity Medical Center Groningen, Department of Surgery, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.ORCID 0000-0002-2236-5233
Stefan P BergerUniversity Medical Centre Groningen, Department of Internal Medicine, Division of Nephrology, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.ORCID 0000-0003-2228-4676
Henri G D LeuveninkUniversity Medical Center Groningen, Department of Surgery, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
Michel M R F StruysUniversity Medical Center Groningen, Department of Anesthesiology, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
Gertrude J Nieuwenhuijs-MoekeUniversity Medical Center Groningen, Department of Anesthesiology, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.ORCID 0000-0001-9874-2632
University Medical Center Groningen · NL

Funding

University Medical Center Groningen 684000
6 · The paper itself

Abstract

Early non-invasive detection and prediction of graft function after kidney transplantation is essential since interventions might prevent further deterioration. The aim of this study was to analyze the dynamics and predictive value of four urinary biomarkers: kidney injury molecule-1 (KIM-1), heart-type fatty acid binding protein (H-FABP), N-acetyl-β-D-glucosaminidase (NAG), and neutrophil gelatinase-associated lipocalin (NGAL) in a living donor kidney transplantation (LDKT) cohort. Biomarkers were measured up to 9 days after the transplantation of 57 recipients participating in the VAPOR-1 trial. Dynamics of KIM-1, NAG, NGAL, and H-FABP significantly changed over the course of 9 days after transplantation. KIM-1 at day 1 and NAG at day 2 after transplantation were significant predictors for the estimated glomerular filtration rate (eGFR) at various timepoints after transplantation with a positive estimate (

Indexed as

Acute Kidney InjuryKidney TransplantationBiomarkersFatty Acid Binding Protein 3HumansKidneyLipocalin-2Living DonorsBiomarkersFatty Acid Binding Protein 3Lipocalin-2kidney transplantationprediction modelsurinary biomarkers

Identifiers

PMID36982720
PMCPMC10054503
OpenAlexW4327620389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.