Evidence map›Paper›PMID 36982702›Full record

ReviewInternational journal of molecular sciences2023

The Blood Microbiome and Health: Current Evidence, Controversies, and Challenges.

Hong Sheng Cheng, Sin Pei Tan, David Meng Kit Wong, Wei Ling Yolanda Koo, Sunny Hei Wong, Nguan Soon Tan

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 67 citations in OpenAlex.

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  20. Blood microbiome signatures in the REM sleep behavior disorder-Lewy body disease continuum.Journal of neural transmission (Vienna, Austria : 1996) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Hong Sheng ChengLee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore 308232, Singapore.ORCID 0000-0001-9745-7872
Sin Pei TanRadiotherapy and Oncology Department, Hospital Sultan Ismail, Jalan Mutiara Emas Utama, Taman Mount Austin, Johor Bahru 81100, Malaysia.
David Meng Kit WongSchool of Biological Sciences, Nanyang Technological University Singapore, Singapore 637551, Singapore.
Wei Ling Yolanda KooSchool of Biological Sciences, Nanyang Technological University Singapore, Singapore 637551, Singapore.
Sunny Hei WongLee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore 308232, Singapore.ORCID 0000-0002-3354-9310
Nguan Soon TanLee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore 308232, Singapore.ORCID 0000-0003-0136-7341
Nanyang Technological University · SGSultan Ismail Specialist Hospital · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood is conventionally thought to be sterile. However, emerging evidence on the blood microbiome has started to challenge this notion. Recent reports have revealed the presence of genetic materials of microbes or pathogens in the blood circulation, leading to the conceptualization of a blood microbiome that is vital for physical wellbeing. Dysbiosis of the blood microbial profile has been implicated in a wide range of health conditions. Our review aims to consolidate recent findings about the blood microbiome in human health and to highlight the existing controversies, prospects, and challenges around this topic. Current evidence does not seem to support the presence of a core healthy blood microbiome. Common microbial taxa have been identified in some diseases, for instance,

Indexed as

LegionellaMicrobiotaDysbiosisForecastingHost Microbial InteractionsHumansbacterial translocationdysbiosishost–microbe interactionmicrobial commensalismsepticaemia

Identifiers

PMID36982702
PMCPMC10059777
OpenAlexW4327619166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.