Evidence map›Paper›PMID 36982670›Full record

ArticleInternational journal of molecular sciences2023

Evaluation of the Oral Bacterial Genome and Metabolites in Patients with Wolfram Syndrome.

E Zmysłowska-Polakowska, T Płoszaj, S Skoczylas, P Mojsak, M Ciborowski, A Kretowski, M Lukomska-Szymanska, A Szadkowska, W Mlynarski, A Zmysłowska

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

E Zmysłowska-PolakowskaDepartment of Endodontics, Medical University of Lodz, 92-213 Lodz, Poland.ORCID 0000-0001-8959-5757
T PłoszajDepartment of Clinical Genetics, Medical University of Lodz, 92-213 Lodz, Poland.
S SkoczylasDepartment of Clinical Genetics, Medical University of Lodz, 92-213 Lodz, Poland.ORCID 0000-0003-2760-2397
P MojsakClinical Research Centre, Medical University of Bialystok, 15-276 Bialystok, Poland.
M CiborowskiClinical Research Centre, Medical University of Bialystok, 15-276 Bialystok, Poland.ORCID 0000-0003-3729-0518
A KretowskiClinical Research Centre, Medical University of Bialystok, 15-276 Bialystok, Poland.ORCID 0000-0002-4522-4978
M Lukomska-SzymanskaDepartment of General Dentistry, Medical University of Lodz, 92-213 Lodz, Poland.ORCID 0000-0002-6110-4298
A SzadkowskaDepartment of Pediatrics, Diabetology, Endocrinology and Nephrology, Medical University of Lodz, 92-213 Lodz, Poland.
W MlynarskiDepartment of Pediatrics, Oncology and Hematology, Medical University of Lodz, 92-213 Lodz, Poland.ORCID 0000-0003-2714-5851
A ZmysłowskaDepartment of Clinical Genetics, Medical University of Lodz, 92-213 Lodz, Poland.ORCID 0000-0001-8781-4469
Medical University of Lodz · PLMedical University of Białystok · PL

Funding

National Science Center 2015/19/B/NZ5/02243
6 · The paper itself

Abstract

In Wolfram syndrome (WFS), due to the loss of wolframin function, there is increased ER stress and, as a result, progressive neurodegenerative disorders, accompanied by insulin-dependent diabetes. The aim of the study was to evaluate the oral microbiome and metabolome in WFS patients compared with patients with type 1 diabetes mellitus (T1DM) and controls. The buccal and gingival samples were collected from 12 WFS patients, 29 HbA1c-matched T1DM patients (

Indexed as

Diabetes Mellitus, Type 1Wolfram SyndromeGenome, BacterialHumansMetabolomeRNA, Ribosomal, 16SRNA, Ribosomal, 16Sgingival samplesmetabolomicsneurodegenerationoral microbiomeWolfram syndrome

Identifiers

PMID36982670
PMCPMC10053501
OpenAlexW4324385517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.