Trial reportInternational journal of molecular sciences2023
A Histologic, Histomorphometric, and Immunohistochemical Evaluation of Anorganic Bovine Bone and Injectable Biphasic Calcium Phosphate in Humans: A Randomized Clinical Trial.
Trial report in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- New bone formation of biphasic calcium phosphate bone substitute material: a systematic review and network meta-analysis of randomized controlled trials (RCTs).International journal of implant dentistry · 2025Pooled it
- Hydroxyapatite composite sodium hyaluronate for alveolar ridge preservation: a prospective, randomized, parallel-controlled, single-blind, non-inferiority multicenter clinical trial.Clinical oral investigations · 2026Trial
- Comparative Analysis of Bone Remodeling Dynamics and Bone Vitality Following Standard Bone Augmentation Procedures: A Review.Journal of functional biomaterials · 2026Review
- Selenium-Loaded Calcium Phosphate with Long-Term and Curative Dosage Drug Release for Post-Surgical Osteosarcoma Management and Osteogenesis.International journal of molecular sciences · 2026Article
- Digital Manufacturing of Calcium Phosphate-Based Dental Materials: From Design to Clinical Use.Materials (Basel, Switzerland) · 2026Review
- Harnessing and Optimizing α-TCP for Oral Tissue Engineering and Regenerative Dentistry.International dental journal · 2026Review
- Synthetic Biomaterials for Alveolar Bone Regeneration: A Systematic Review of Clinical Evidence.Materials (Basel, Switzerland) · 2025Review
- Mechanically tunable fiber-based hydrogel activates PIEZO1-integrin axis for enhanced bone repair.Journal of nanobiotechnology · 2025Article
- Efficacy of Three-Dimensional Bioactive Composites in Long Bone Repair with Photobiomodulation.Materials (Basel, Switzerland) · 2025Article
- A new eggshell-derived calcium phosphate bioceramic for tissue engineering: cytotoxicity and histomorphometric study.Acta cirurgica brasileira · 2025Article
- Histomorphometric Analysis of Osseointegrated Intraosseous Dental Implants Using Undecalcified Specimens: A Scoping Review.Biomimetics (Basel, Switzerland) · 2024Article
- Cuttlefish Bone-Derived Calcium Phosphate Bioceramics Have Enhanced Osteogenic Properties.Journal of functional biomaterials · 2024Article
- Developments in Alloplastic Bone Grafts and Barrier Membrane Biomaterials for Periodontal Guided Tissue and Bone Regeneration Therapy.International journal of molecular sciences · 2024Review
- Resorption Rates of Bone Graft Materials after Crestal Maxillary Sinus Floor Elevation and Its Influencing Factors.Journal of functional biomaterials · 2024Article
- From Basic Science to Clinical Practice: A Review of Current Periodontal/Mucogingival Regenerative Biomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Regeneration of Buccal Wall Defects after Tooth Extraction with Biphasic Calcium Phosphate in Injectable Form vs. Bovine Xenograft: A Randomized Controlled Clinical Trial.Dentistry journal · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Following trauma, chronic periapical process, or tooth extraction, a large loss of bone volume is noticed during the healing process. To facilitate the placement of dental implants, various surgical procedures are used for an optimal alveolar ridge profile, while maintaining adequate bone dimensions. The main aim of this study was to determine the healing ability (histologically and immunohistologically) of alveolar bone defects during augmentation with two different biomaterials: injectable biphasic calcium phosphate (BCP) and anorganic bovine bone (ABB). Thirty-eight subjects were randomly divided into two groups. The first group received the tested bone substitute biomaterial (BSB), i.e., BCP (maxresorb inject
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.