Evidence map›Paper›PMID 36982575›Full record

ReviewInternational journal of molecular sciences2023

Role of Adhesion G Protein-Coupled Receptors in Immune Dysfunction and Disorder.

Wen-Yi Tseng, Martin Stacey, Hsi-Hsien Lin

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Adhesion G protein-coupled receptors.Pharmacological reviews · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Wen-Yi TsengDivision of Rheumatology, Allergy, and Immunology, Chang Gung Memorial Hospital-Keelung, Keelung 20401, Taiwan.ORCID 0000-0001-9073-2253
Martin StaceyFaculty of Biological Sciences, School of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, UK.
Hsi-Hsien LinDivision of Rheumatology, Allergy, and Immunology, Chang Gung Memorial Hospital-Keelung, Keelung 20401, Taiwan.ORCID 0000-0003-2798-3855
Chang Gung University · TWUniversity of Leeds · GB

Funding

Chang Gung Memorial Hospital CMRPG2K0262, CMRPG2M0291, CMRPG2K0172, CMRPG2M0301, CMRPD1M0032, CMRPD1M0511, CMRPD1M0521, CMRPD1M0321National Science and Technology Council, Taiwan NSTC-111-2314-B-182-028, NSTC-110-2320-B-182-024
6 · The paper itself

Abstract

Disorders of the immune system, including immunodeficiency, immuno-malignancy, and (auto)inflammatory, autoimmune, and allergic diseases, have a great impact on a host's health. Cellular communication mediated through cell surface receptors, among different cell types and between cell and microenvironment, plays a critical role in immune responses. Selective members of the adhesion G protein-coupled receptor (aGPCR) family are expressed differentially in diverse immune cell types and have been implicated recently in unique immune dysfunctions and disorders in part due to their dual cell adhesion and signaling roles. Here, we discuss the molecular and functional characteristics of distinctive immune aGPCRs and their physiopathological roles in the immune system.

Indexed as

NeoplasmsReceptors, G-Protein-CoupledCell AdhesionHumansSignal TransductionTumor MicroenvironmentReceptors, G-Protein-Coupledadhesion GPCRsimmune disorderimmune dysfunctionligandsignaling

Identifiers

PMID36982575
PMCPMC10055975
OpenAlexW4324144367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.