Evidence map›Paper›PMID 36982481›Full record

ReviewInternational journal of molecular sciences2023

Room Temperature Synthesis of Bioactive 1,2,4-Oxadiazoles.

Sergey V Baykov, Anton A Shetnev, Artem V Semenov, Svetlana O Baykova, Vadim P Boyarskiy

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Synthesis of 1,2,4-Oxadiazin-5(6Molecules (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Bioactive Oxadiazoles 3.0.International journal of molecular sciences · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sergey V BaykovInstitute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., 199034 Saint Petersburg, Russia.ORCID 0000-0002-8912-5816
Anton A ShetnevPharmaceutical Technology Transfer Centre, Yaroslavl State Pedagogical University Named after K.D. Ushinsky, 108 Respublikanskaya St., 150000 Yaroslavl, Russia.ORCID 0000-0002-4389-461X
Artem V SemenovInstitute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., 199034 Saint Petersburg, Russia.ORCID 0000-0003-4647-7018
Svetlana O BaykovaInstitute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., 199034 Saint Petersburg, Russia.
Vadim P BoyarskiyInstitute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., 199034 Saint Petersburg, Russia.ORCID 0000-0002-6038-0872

Funding

Russian Science Foundation 22-73-10031
6 · The paper itself

Abstract

1,2,4-Oxadiazole is an essential motif in drug discovery represented in many experimental, investigational, and marketed drugs. This review covers synthetic methods that allow the conversion of different types of organic compounds into 1,2,4-oxadiazole at ambient temperature and the practical application of the latter approaches for the preparation of pharmaceutically important molecules. The discussed methods are divided into three groups. The first combines two-stage protocols requiring the preliminary preparation of

Indexed as

Drug DesignOxadiazolesCyclizationDrug DiscoveryTemperatureOxadiazoles1,2,4-oxadiazoleamidoximesbase catalyzed cyclizationbioactive compoundsbioisosteresoxidative cyclizationroom temperature

Identifiers

PMID36982481
PMCPMC10056168

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.