Evidence map›Paper›PMID 36982372›Full record

ArticleInternational journal of molecular sciences2023

Anti-Inflammatory Effects and Photo- and Neuro-Protective Properties of BIO203, a New Amide Conjugate of Norbixin, in Development for the Treatment of Age-Related Macular Degeneration (AMD).

Valérie Fontaine, Christine Balducci, Laurence Dinan, Elodie Monteiro, Thinhinane Boumedine, Mylène Fournié, Vincent Nguyen, Louis Guibout, Justine Clatot, Mathilde Latil and 5 more

Open access · goldFull text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Valérie FontaineSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Christine BalducciBiophytis, Sorbonne Université, BC9, 4 Place Jussieu, 75005 Paris, France.
Laurence DinanBiophytis, Sorbonne Université, BC9, 4 Place Jussieu, 75005 Paris, France.
Elodie MonteiroSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Thinhinane BoumedineSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Mylène FourniéSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Vincent NguyenSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Louis GuiboutBiophytis, Sorbonne Université, BC9, 4 Place Jussieu, 75005 Paris, France.
Justine ClatotBiophytis, Sorbonne Université, BC9, 4 Place Jussieu, 75005 Paris, France.
Mathilde LatilBiophytis, Sorbonne Université, BC9, 4 Place Jussieu, 75005 Paris, France.
Stanislas VeilletBiophytis, Sorbonne Université, BC9, 4 Place Jussieu, 75005 Paris, France.
José-Alain SahelSorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
René LafontBiophytis, Sorbonne Université, BC9, 4 Place Jussieu, 75005 Paris, France.
Pierre J DildaBiophytis, Sorbonne Université, BC9, 4 Place Jussieu, 75005 Paris, France.
Serge CameloBiophytis, Sorbonne Université, BC9, 4 Place Jussieu, 75005 Paris, France.ORCID 0000-0001-8733-8503
Sorbonne Université · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

9'-

Indexed as

Macular DegenerationRetinal DegenerationAnimalsAnti-Inflammatory AgentsATP-Binding Cassette TransportersCarotenoidsMiceRatsRetinal Pigment EpitheliumRetinoidsAbca4 protein, mouseAnti-Inflammatory AgentsATP-Binding Cassette TransportersCarotenoidsnorbixinRetinoidsA2EAMDeyenorbixin-conjugatepharmacokineticsPPARsRPE

Identifiers

PMID36982372
PMCPMC10049354
OpenAlexW4323849783

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read112
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.