Evidence map›Paper›PMID 36982269›Full record

ArticleInternational journal of molecular sciences2023

Identification of Three Human POLH Germline Variants Defective in Complementing the UV- and Cisplatin-Sensitivity of POLH-Deficient Cells.

Mina Yeom, Jin-Kyung Hong, Joo-Ho Shin, Yunjong Lee, Frederick Peter Guengerich, Jeong-Yun Choi

Open access · goldFull text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mina YeomDepartment of Pharmacology, Sungkyunkwan University School of Medicine, Suwon 16419, Republic of Korea.
Jin-Kyung HongDepartment of Pharmacology, Sungkyunkwan University School of Medicine, Suwon 16419, Republic of Korea.ORCID 0000-0003-1302-9462
Joo-Ho ShinDepartment of Pharmacology, Sungkyunkwan University School of Medicine, Suwon 16419, Republic of Korea.ORCID 0000-0002-0499-4589
Yunjong LeeDepartment of Pharmacology, Sungkyunkwan University School of Medicine, Suwon 16419, Republic of Korea.ORCID 0000-0003-0182-2279
Frederick Peter GuengerichDepartment of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232-0146, USA.ORCID 0000-0002-7458-3048
Jeong-Yun ChoiDepartment of Pharmacology, Sungkyunkwan University School of Medicine, Suwon 16419, Republic of Korea.
Sungkyunkwan University · KRVanderbilt University · US

Funding

BIOACTIVATION OF HALOGENATED HYDROCARBONSR01ES010546 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 2001 to 2020
$8.1M
NIEHS NIH HHS R01 ES010546NIH HHS R01 ES010546
6 · The paper itself

Abstract

DNA polymerase (pol) η is responsible for error-free translesion DNA synthesis (TLS) opposite ultraviolet light (UV)-induced

Indexed as

CisplatinXeroderma PigmentosumDNADNA DamageDNA-Directed DNA PolymeraseDNA RepairGerm CellsHumansUltraviolet RaysCisplatinDNADNA-Directed DNA PolymerasecisplatinDNA polymerase ηgermline varianttranslesion DNA synthesisUVXPV

Identifiers

PMID36982269
PMCPMC10048814
OpenAlexW4323665005

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read23
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.