Evidence map›Paper›PMID 36982201›Full record

ArticleInternational journal of molecular sciences2023

Repeated Application and Removal of Polyisocyanopeptide Hydrogel Wound Dressings in a Splinted Full-Thickness Wound Model.

Roel C Op 't Veld, Lieke Joosten, Peter Laverman, Ewald M Bronkhorst, John A Jansen, X Frank Walboomers, Frank A D T G Wagener

Full text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roel C Op 't VeldDepartment of Dentistry-Biomaterials, Research Institute for Medical Innovation, Radboud University Medical Centre, 6525 EX Nijmegen, The Netherlands.
Lieke JoostenDepartment of Medical Imaging, Nuclear Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.ORCID 0000-0003-4427-8664
Peter LavermanDepartment of Medical Imaging, Nuclear Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Ewald M BronkhorstDepartment of Dentistry, Research Institute for Medical Innovation, Radboud University Medical Centre, 6525 EX Nijmegen, The Netherlands.ORCID 0000-0003-0953-8053
John A JansenDepartment of Dentistry-Biomaterials, Research Institute for Medical Innovation, Radboud University Medical Centre, 6525 EX Nijmegen, The Netherlands.ORCID 0000-0003-3077-8617
X Frank WalboomersDepartment of Dentistry-Biomaterials, Research Institute for Medical Innovation, Radboud University Medical Centre, 6525 EX Nijmegen, The Netherlands.
Frank A D T G WagenerDepartment of Dentistry-Orthodontics and Craniofacial Biology, Research Institute for Medical Innovation, Radboud University Medical Centre, Philips van Leydenlaan 25, 6525 EX Nijmegen, The Netherlands.ORCID 0000-0003-4837-1559

Funding

Netherlands Organisation for Health Research and Development ZonMW #436001005
6 · The paper itself

Abstract

Polyisocyanopeptide (PIC) hydrogels are proposed as promising wound dressings. These gels are thermo-sensitive, allow application as a cold liquid, and rely on gelation through body heat. It is supposed that the gel can be easily removed by reversing the gelation and washing it away with a cold irrigation solution. The impact on wound healing of the regular application and removal of PIC dressings is compared to a single application of PIC and the clinically used Tegaderm™ in murine splinted full-thickness wounds for up to 14 days. SPECT/CT analysis of

Indexed as

HydrogelsWound HealingAnimalsBandagesHumansMicePolyvinyl AlcoholPovidoneHydrogelsPolyvinyl AlcoholPovidonehydrogel wound dressingpolyisocyanopeptide

Identifiers

PMID36982201
PMCPMC10049480

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.