Evidence map›Paper›PMID 36982197›Full record

ArticleInternational journal of molecular sciences2023

The Enzyme 15-Hydroxyprostaglandin Dehydrogenase Inhibits a Shift to the Mesenchymal Pattern of Trophoblasts and Decidual Stromal Cells Accompanied by Prostaglandin Transporter in Preeclampsia.

Huiyuan Pang, Di Lei, Tingting Chen, Yujie Liu, Cuifang Fan

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Huiyuan PangDepartment of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Di LeiDepartment of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Tingting ChenDepartment of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Yujie LiuDepartment of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Cuifang FanDepartment of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Renmin Hospital of Wuhan University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preeclampsia (PE) is a pregnancy complication beginning after 20 weeks of pregnancy that involves high blood pressure (systolic > 140 mmHg or diastolic > 90 mmHg), with or without proteinuria. Insufficient trophoblast invasion and abnormal decidualization are involved in PE development. However, whether unhealthy placenta and decidua have the same biological activities is unclear. The enzyme 15-hydroxyprostaglandin dehydrogenase (15-PGDH; encoded by

Indexed as

PlacentaPre-EclampsiaDeciduaDinoprostoneFemaleHumansHydroxyprostaglandin DehydrogenasesPregnancyStromal CellsTrophoblasts15-hydroxyprostaglandin dehydrogenaseDinoprostoneHydroxyprostaglandin Dehydrogenases15-PGDHdeciduaEMTMETPGTplacentapreeclampsia

Identifiers

PMID36982197
PMCPMC10049104
OpenAlexW4323566433

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read37
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.