Evidence map›Paper›PMID 36982186›Full record

ArticleInternational journal of molecular sciences2023

Differential Transcriptome Responses in Human THP-1 Macrophages Following Exposure to T98G and LN-18 Human Glioblastoma Secretions: A Simplified Bioinformatics Approach to Understanding Patient-Glioma-Specific Effects on Tumor-Associated Macrophages.

Micaela R Scobie, Abdullah Abood, Charles D Rice

Open access · goldFull text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Micaela R ScobieDurham Veterans Health Administration Medical Center, Durham, NC 27705, USA.ORCID 0000-0002-9217-0562
Abdullah AboodDepartment of Biochemistry and Molecular Genetics, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.ORCID 0000-0001-5714-6375
Charles D RiceDepartment of Biological Sciences, Clemson University, Clemson, SC 29634, USA.ORCID 0000-0002-5352-9165
Clemson University · USUniversity of Virginia · USVeterans Health Administration · US

Funding

Self-Regional Healthcare Human Genetics Research Program, Greenwood Genetics Center, Greenwood SC USA 04262016
6 · The paper itself

Abstract

A common theme in glioma disease progression is robust infiltration of immune cells within the tumor microenvironment, resulting in a state of chronic inflammation. This disease state is characterized by an abundance of CD68

Indexed as

GlioblastomaGliomaComputational BiologyHumansMacrophagesTranscriptomeTumor-Associated MacrophagesTumor MicroenvironmentLN-18 gliomaT98G gliomaTHP-1 macrophagetranscriptomicstumor microenvironment

Identifiers

PMID36982186
PMCPMC10049238
OpenAlexW4323566427

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read13
table measurements read9
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.