Evidence map›Paper›PMID 36982146›Full record

ArticleInternational journal of molecular sciences2023

Neurodegenerative Changes in the Brains of the 5xFAD Alzheimer's Disease Model Mice Investigated by High-Field and High-Resolution Magnetic Resonance Imaging and Multi-Nuclei Magnetic Resonance Spectroscopy.

Chi-Hyeon Yoo, Jinho Kim, Hyeon-Man Baek, Keun-A Chang, Bo-Young Choe

Open access · goldFull text read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Diffusion MRI reveals amyloid plaque-associated cellular signatures through spatial transcriptomic integration.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Chi-Hyeon YooAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.ORCID 0000-0001-5234-4583
Jinho KimDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences & Technology, Gachon University, Incheon 21999, Republic of Korea.
Hyeon-Man BaekDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences & Technology, Gachon University, Incheon 21999, Republic of Korea.
Keun-A ChangDepartment of Health Sciences and Technology, Gachon Advanced Institute for Health Sciences & Technology, Gachon University, Incheon 21999, Republic of Korea.ORCID 0000-0002-6157-6340
Bo-Young ChoeDepartment of Biomedicine & Health Sciences, Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Gachon University · KRCatholic University of Korea · KRHarvard University · US

Funding

Korea Basic Science Institute 2021R1A6C101A432National Research Foundation of Korea 2020M3A9E4104384National Research Foundation of Korea 2022R1A2C1092597
6 · The paper itself

Abstract

This study aimed to investigate morphological and metabolic changes in the brains of 5xFAD mice. Structural magnetic resonance imaging (MRI) and

Indexed as

Alzheimer DiseaseAnimalsBrainDisease Models, AnimalGray MatterMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMiceMice, TransgenicAlzheimer’s diseaseamyloid plaqueshigh-resolution MRIinflammationmetabolic investigationmorphologic investigationproton and phosphorus MRS

Identifiers

PMID36982146
PMCPMC10049146
OpenAlexW4323362817

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read26
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.