ArticleInternational journal of molecular sciences2023
Swelling of Homogeneous Alginate Gels with Multi-Stimuli Sensitivity.
Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 47 citations in OpenAlex.
- Additive-Mediated Stability Enhancement of Bakuchiol-Loaded Alginate Core-Shell Microcapsules Fabricated by Coaxial Electrospray.ACS omega · 2026Article
- Comparative Evaluation of Machine Learning-Assisted Statistical Modeling of Biopolymer Hydrogel Swelling for Material Optimization.ACS omega · 2026Article
- Aqueous Two-Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells.Advanced healthcare materials · 2026Article
- 3D-Printed Alginate Dialdehyde (ADA)-Gelatin (GEL) Hydrogels with Gallic Acid (GA) for Enhanced Multifunctional Properties.ACS omega · 2026Article
- Polymer-Gated Bilayer Buccoadhesive Tablets for Biphasic Release of Indomethacin: Balancing Dissolution and Mucoadhesion.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Facile and Green Fabrication of Porous Hydrogels Based on Gelatin Microsphere Porogens for 3D Immune Cell Culture.Gels (Basel, Switzerland) · 2026Article
- Development of Eco-Friendly Hydrogels Loaded with Stoichiometric and Calcium-Deficient Hydroxyapatites for Sustainable Agriculture.ACS applied materials & interfaces · 2026Article
- Synergistic SA/Pebax composite membranes on ceramic supports for efficient ethanol-water separation.RSC advances · 2026Article
- Development of In Situ Gelling Liquid Extended Release System for Oral Delivery of Abiraterone Acetate.AAPS PharmSciTech · 2026Article
- Influence of Deep Eutectic Solvents and Polyphenolic Extracts on the Structure and Functional Properties of Sodium Alginate Films.Polymers · 2026Article
- Swelling Property and Metal Adsorption of Dialdehyde Crosslinked Poly Aspartate/Alginate Gel Beads.Polymers · 2026Article
- Effect of Sodium Alginate Concentration on the Physicochemical, Structural, Functional Attributes, and Consumer Acceptability of Gel Beads Encapsulating Tangerine Peel (Gels (Basel, Switzerland) · 2025Article
- Whey Protein Isolate and β-Lactoglobulin-Modified Alginate Hydrogel Scaffolds Enhance Cell Proliferation for Cultivated Meat Applications.Foods (Basel, Switzerland) · 2025Article
- Innovative Ink-Based 3D Hydrogel Bioprinted Formulations for Tissue Engineering Applications.Gels (Basel, Switzerland) · 2024Article
- Encapsulation in Alginates Hydrogels and Controlled Release: An Overview.Molecules (Basel, Switzerland) · 2024Review
- The Effect of pH on the Viscoelastic Response of Alginate-Montmorillonite Nanocomposite Hydrogels.Molecules (Basel, Switzerland) · 2024Article
- Role of Polymer Concentration on the Release Rates of Proteins from Single- and Double-Network Hydrogels.International journal of molecular sciences · 2023Article
- The Effect of Temperature on the Mechanical Properties of Alginate Gels in Water/Alcohol Solutions.Gels (Basel, Switzerland) · 2023Article
- Article
- Hollow Particles Obtained by Prilling and Supercritical Drying as a Potential Conformable Dressing for Chronic Wounds.Gels (Basel, Switzerland) · 2023Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
A new two-step method is suggested for the preparation of homogeneous alginate gels. In the first step, alginate chains are weakly bonded by Ca2+ ions in an aqueous solution with a low pH. In the next step, the gel is immersed into a strong solution of CaCl2 to finalize the cross-linking process. Homogeneous alginate gels preserve their integrity in aqueous solutions with a pH ranging from 2 to 7 and ionic strength in the interval from 0 to 0.2 M, at temperatures ranging from room temperature up to 50 °C, and can be used in biomedical applications. The immersion of these gels into aqueous solutions with low pH induces the partial breakage of ionic bonds between chains (treated as gel degradation). This degradation affects the equilibrium and transient swelling of homogeneous alginate gels and makes them sensitive to the history of loading and environmental conditions (pH, ionic strength and temperature of aqueous solutions). As sensitivity to the environmental stimuli is a characteristic feature of polymer networks connected by catch bonds, homogeneous alginate gels may serve as a simple model, mimicking the behavior of more sophisticated structures in living matter.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.