Evidence map›Paper›PMID 36982042›Full record

ArticleInternational journal of environmental research and public health2023

Sedentary Behaviour and Telomere Length Shortening during Early Childhood: Evidence from the Multicentre Prospective INMA Cohort Study.

Daniel Prieto-Botella, Dries S Martens, Desiree Valera-Gran, Mikel Subiza-Pérez, Adonina Tardón, Manuel Lozano, Maribel Casas, Mariona Bustamante, Alba Jimeno-Romero, Ana Fernández-Somoano and 4 more

Full text readMulticenter Study
In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Prolonged exposure to leisure screen time notably accelerates biological aging: Evidence from observational studies and genetic associations.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniel Prieto-BotellaDepartment of Surgery and Pathology, Miguel Hernandez University, 03550 Alicante, Spain.ORCID 0000-0003-0973-4492
Dries S MartensCentre for Environmental Sciences, Hasselt University, Agoralaan Gebouw D, BE-3590 Hasselt, Belgium.
Desiree Valera-GranDepartment of Surgery and Pathology, Miguel Hernandez University, 03550 Alicante, Spain.ORCID 0000-0001-6388-127X
Mikel Subiza-PérezBiodonostia Health Research Institute, Group of Environmental Epidemiology and Child Development, 20014 San Sebastian, Spain.ORCID 0000-0002-6843-8557
Adonina TardónUnidad de Epidemiología Molecular del Cáncer, Departamento de Medicina, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, Julián Clavería Street s/n, 33006 Oviedo, Spain.ORCID 0000-0001-5150-1209
Manuel LozanoEpidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, 46020 Valencia, Spain.ORCID 0000-0003-2046-5959
Maribel CasasSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.
Mariona BustamanteSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.
Alba Jimeno-RomeroDepartment of Preventive Medicine and Public Health, Faculty of Medicine, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.ORCID 0000-0003-1024-0190
Ana Fernández-SomoanoSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0002-8135-9079
Sabrina LlopSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.
Martine VrijheidSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain.
Tim S NawrotCentre for Environmental Sciences, Hasselt University, Agoralaan Gebouw D, BE-3590 Hasselt, Belgium.
Eva-María Navarrete-MuñozDepartment of Surgery and Pathology, Miguel Hernandez University, 03550 Alicante, Spain.ORCID 0000-0002-1494-5676

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sedentary behaviour (SB) may be related to telomere length (TL) attrition due to a possible pro-inflammatory effect. This study examined the association between parent-reported sedentary behaviour (SB) and leukocyte TL at the age of 4 and telomere tracking from 4 to 8 years. In the Spanish birth cohort Infancia y Medio Ambiente (INMA) project, we analysed data from children who attended follow-up visits at age 4 (n = 669) and 8 (n = 530). Multiple robust regression models were used to explore the associations between mean daily hours of SB (screen time, other sedentary activities, and total SB) at 4 years categorised into tertiles and TL at 4 years and difference in TL rank between age 4 and 8, respectively. At the age of 4, the results showed that children with the highest screen time (1.6-5.0 h/day) had a shorter TL of -3.9% (95% CI: -7.4, -0.4;

Indexed as

Sedentary BehaviorTelomereChildChild, PreschoolCohort StudiesHumansLeukocytesLongitudinal StudiesProspective Studiescellular longevitychildrenepigeneticsgeneticslifestylescreen time

Identifiers

PMID36982042
PMCPMC10048855

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.