Evidence map›Paper›PMID 36981846›Full record

Trial reportInternational journal of environmental research and public health2023

Multimodal Physical Exercise and Functional Rehabilitation Program in Oncological Patients with Cancer-Related Fatigue-A Randomized Clinical Trial.

Eduardo J Fernandez-Rodriguez, Celia Sanchez-Gomez, Roberto Mendez-Sanchez, Jose I Recio-Rodriguez, A Silvia Puente-Gonzalez, Jesus Gonzalez-Sanchez, Juan J Cruz-Hernandez, Maria I Rihuete-Galve

Open access · goldFull text readRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Asthenia in cancer patients receiving immune checkpoint Inhibitors (ICIs): the MOUSEION-11 systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  4. Article
  5. Physiotherapy in the primary care oncology team.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026
    Review
  6. Toward precision rehabilitation: a latent profile analysis of social support as a buffer against fatigue and reduced physical activity in breast cancer chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Eduardo J Fernandez-RodriguezDepartment of Nursing and Physiotherapy, University of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-2175-8545
Celia Sanchez-GomezInstituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0002-1196-816X
Roberto Mendez-SanchezDepartment of Nursing and Physiotherapy, University of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-4486-4076
Jose I Recio-RodriguezDepartment of Nursing and Physiotherapy, University of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0002-3772-8746
A Silvia Puente-GonzalezDepartment of Nursing and Physiotherapy, University of Salamanca, 37007 Salamanca, Spain.
Jesus Gonzalez-SanchezDepartment of Nursing and Physiotherapy, University of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0001-5453-2510
Juan J Cruz-HernandezInstituto de Investigación Biomédica de Salamanca (IBSAL), 37007 Salamanca, Spain.ORCID 0000-0003-1980-2751
Maria I Rihuete-GalveDepartment of Nursing and Physiotherapy, University of Salamanca, 37007 Salamanca, Spain.
Universidad de Salamanca · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase in life expectancy and survival time implies an increase in the possible side-effects of pharmacological treatments in patients. Cancer-related fatigue is one of these side-effects. The main objective of this study was to evaluate the effects of a multimodal program of physical exercise and functional rehabilitation on asthenia, pain, functional capacity, and quality of life in cancer patients with cancer-related fatigue.

methodsThis was a randomized, parallel-controlled clinical trial, with two arms (experimental and control group), and it was conducted over the course of a year in the Oncology Hospitalization Unit at the University Hospital of Salamanca, Spain. Participants (n = 48) were assessed at three points during the study. The first assessment was prior to hospital discharge, the second assessment was after 15 days, and the final assessment was at one month post-hospital follow-up. The intervention lasted one month. The main variables studied were the dependency levels (Barthel), cancer-related fatigue (FACT-An), health-related quality of life (EuroQoL-5D), functional capacity (SPPB), and kinesiophobia (TSK-F).

resultsSample size (n = 44). Mean age 63.46 ± 12.36 years. Significant differences between control and experimental group participants in Barthel, FACT-An, TSK-F, and SPPB scores at follow-up and final assessment.

conclusionsThere are beneficial effects of a multimodal physical exercise and functional rehabilitation program in improving the autonomy of cancer-related fatigue patients.

Indexed as

Exercise TherapyNeoplasmsPhysical Therapy ModalitiesAgedCombined Modality TherapyFatigueFemaleHumansMaleMiddle AgedQuality of LifeTreatment Outcomecancerdisabilityexercisemultidisciplinaryquality of liferehabilitation

Identifiers

PMID36981846
PMCPMC10049732
OpenAlexW4324093666

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read10
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.