Evidence map›Paper›PMID 36981793›Full record

ArticleInternational journal of environmental research and public health2023

Synthesis, Characterization and Application of a MIP-polyHIPE for Selective Extraction of Angiotensin II Receptor Antagonists Residues in Natural Waters.

Andrea Speltini, Giancarla Alberti, Riccardo Rovida, Chiara Milanese, Giulia De Soricellis, Francesca Rinaldi, Gabriella Massolini, Angelo Gallo, Enrica Calleri

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In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Andrea SpeltiniDepartment of Chemistry, University of Pavia, via Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-6924-7170
Giancarla AlbertiDepartment of Chemistry, University of Pavia, via Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0003-4106-2219
Riccardo RovidaDepartment of Chemistry, University of Pavia, via Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-5984-7885
Chiara MilaneseDepartment of Chemistry, University of Pavia, via Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-3763-6657
Giulia De SoricellisDepartment of Drug Sciences, University of Pavia, via Taramelli 12, 27100 Pavia, Italy.
Francesca RinaldiDepartment of Drug Sciences, University of Pavia, via Taramelli 12, 27100 Pavia, Italy.
Gabriella MassoliniDepartment of Drug Sciences, University of Pavia, via Taramelli 12, 27100 Pavia, Italy.
Angelo GalloDepartment of Chemistry, University of Turin, via Pietro Giuria 7, 10125 Turin, Italy.ORCID 0000-0001-9778-4822
Enrica CalleriDepartment of Drug Sciences, University of Pavia, via Taramelli 12, 27100 Pavia, Italy.
University of Pavia · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymers via high internal phase emulsion (polyHIPEs) were molecularly imprinted with Irbesartan, an antihypertensive drug belonging to the class of angiotensin II receptor antagonists (sartan drugs), chosen for the proof-of-concept extraction of hazardous emerging contaminants from water. Different analyte-functional monomer molar ratios (1:100, 1:30 and 1:15) were investigated, and the MIP polyHIPEs have been characterized, parallel to the not imprinted polymer (NIP), by batch sorption experiments. The material with the highest template-functional monomer ratio was the best for Irbesartan removal, showing a sorption capacity fivefold higher than the NIP. Regarding the adsorption kinetics, the analyte-sorbent equilibrium was reached after about 3 h, and the film diffusion model best fitted the kinetic profile. Selectivity was further demonstrated by testing Losartan, another sartan drug, observing a fourfold lower sorption capacity, but still higher than that of NIP. The polymers were also synthesized in cartridges for solid-phase extraction (SPE), which was helpful for evaluating the breakthrough curves and performing pre-concentrations. These have been done in tap and river water samples (100-250 mL, 15-500 µg L

Indexed as

Molecular ImprintingAdsorptionAngiotensin II Type 1 Receptor BlockersAngiotensin II Type 2 Receptor BlockersAngiotensin Receptor AntagonistsChromatography, High Pressure LiquidIrbesartanPolymersSolid Phase ExtractionStyrenesWaterAngiotensin II Type 1 Receptor BlockersAngiotensin II Type 2 Receptor BlockersAngiotensin Receptor AntagonistsIrbesartanpolyHIPEPolymersStyrenesWaterenvironmental watersmolecularly imprinted polymerspharmaceuticalspollutantspolyHIPEsolid-phase extractionwater purification

Identifiers

PMID36981793
PMCPMC10049482
OpenAlexW4323846635

What OpenQuestion holds

Textfull text, public
LicenceCC BY
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.