Evidence map›Paper›PMID 36981696›Full record

ArticleInternational journal of environmental research and public health2023

Preliminary Assessment of In Vivo Raman Spectroscopy Technique for Bone Quality Evaluation of Augmented Maxillary Sinus Floor.

Eduard Gatin, Pal Nagy, Stefan Marian Iordache, Ana-Maria Iordache, Catalin Romeo Luculescu, Valeriy Grygorovskyy

Open access · goldFull text read
In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Eduard GatinFaculty of Medicine, University of Medicine and Pharmacy "Carol Davila", Blv. Eroii Sanitari 8, Sector 5, 050474 Bucharest, Romania.
Pal NagyFaculty of Dentistry, Periodontology Department, Semmelweiss University, 1085 Budapest, Hungary.ORCID 0000-0001-5452-7666
Stefan Marian IordacheOptospintronics Department, National Institute for Research and Development for Optoelectronics-INOE 2000, 077125 Magurele, Romania.ORCID 0000-0002-9840-9896
Ana-Maria IordacheOptospintronics Department, National Institute for Research and Development for Optoelectronics-INOE 2000, 077125 Magurele, Romania.ORCID 0000-0003-4705-0606
Catalin Romeo LuculescuCETAL Department, National Institute for Laser, Plasma and Radiation Physics, Atomistilor Str. 409, 077125 Magurele, Romania.ORCID 0000-0001-6852-401X
Valeriy GrygorovskyyResearch Institute for Traumatology and Orthopedics, 01601 Kyiv, Ukraine.
National Institute of Research and Development for Optoelectronics · RONational Institute for Laser Plasma and Radiation Physics · ROSemmelweis University · HUUniversity of Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: In oral surgery, bone regeneration is achieved through various types of bone grafts or bone substitutes and its success is usually analyzed by micro-computed tomography and histomorphometry. The aim of this study was to evaluate the usefulness of Raman spectroscopy as an alternative to other techniques for bone quality evaluation during a standard oral surgery procedure. (2) Methods: The preliminary evaluation of bone augmentation during maxillary sinus floor elevation oral surgery was performed by Raman spectroscopy for several (five) patients during and after the surgery and the results were compared with postoperative data from histomorphometry, EDX and SEM analysis. (3) Results: After analyzing all the results for the bone samples according to the four methods (Raman, EDX, SEM and Histology) that were used in our study, the obtained result of the investigation provided a good augmentation process for three of the patients and partly successful augmentation process for two of the patients. The primary evaluation using Raman spectroscopy (in vivo and ex vivo investigation) was confirmed by histological results, thus having a first step for validation of Raman as a new method of imaging for dentistry. (4) Conclusions: Our results show that Raman spectroscopy could provide fast and reliable insight on bone condition during augmentation of the maxillary sinus floor. We emphasize the advantages and drawbacks of the proposed techniques as its accuracy could increase by performing larger size clinical trials. Using the Raman mapping, the method can serve as an alternative to histology.

Indexed as

Sinus Floor AugmentationBone TransplantationHumansMaxillary SinusSpectrum Analysis, RamanX-Ray Microtomographybiospectroscopyearly diagnosishistomorphologyin vivo/ex vivo bone evaluationoral regenerative surgeryRaman spectroscopy

Identifiers

PMID36981696
PMCPMC10049299
OpenAlexW4323667817

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read20
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.