ArticleFoods (Basel, Switzerland)2023
Accelerated Accumulation of γ-Aminobutyric Acid and Modifications on Its Metabolic Pathways in Black Rice Grains by Germination under Cold Stress.
Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Germination Time and Temperature Modulate Bioactive Compound Accumulation in Black Rice (Plants (Basel, Switzerland) · 2026Article
- Cold Stress Responses and Adaptation Mechanisms inPlants (Basel, Switzerland) · 2026Review
- Germination Triggers Substantial Changes in GABA, Polyphenol, Sugar, and Organic Acid Content of Commonly Consumed Legumes.Plants (Basel, Switzerland) · 2026Article
- Effects of low-density polyethylene inner liner on keeping the postharvest quality in 'Fuji' apple during storage.Food chemistry: X · 2025Article
- Gamma-Aminobutyric Acid: A Novel Biomolecule to Improve Plant Resistance and Fruit Quality.Plants (Basel, Switzerland) · 2025Review
- Changes in Bioactive Constituents in Black Rice Metabolites Under Different Processing Treatments.Foods (Basel, Switzerland) · 2025Article
- Strategies to Improve γ-Aminobutyric Acid Biosynthesis in Rice via Optimal Conditions.Plants (Basel, Switzerland) · 2025Article
- Integrated Metabolomic and Transcriptomic Analysis Reveals the Molecular Regulatory Mechanism of Gamma-Aminobutyric Acid Accumulation in White Quinoa (Foods (Basel, Switzerland) · 2025Article
- Black rice as the emerging functional food: bioactive compounds, therapeutic potential and industrial applications.Frontiers in nutrition · 2025Review
- Germination alters the bioactive compounds of pigmented and non-pigmented rice varieties in fresh and year-old stored seeds.Food chemistry: X · 2024Article
- Optimization of Germination Conditions for Enriched γ-Aminobutyric Acid and Phenolic Compounds of Foxtail Millet Sprouts by Response Surface Methodology.Foods (Basel, Switzerland) · 2024Article
- Relationship between the GABA Pathway and Signaling of Other Regulatory Molecules.International journal of molecular sciences · 2024Review
- Role of Gamma-Aminobutyric Acid in Plant Defense Response.Metabolites · 2023Review
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Germination can increase γ-aminobutyric acid (GABA) accumulation in grains, but the combined effects of germination and other external stress on rice grains have been little studied. In this investigation, enhanced accumulation of GABA and modification of its metabolic pathways in black rice grains were investigated during germination under cold stress. The combination of cold stress and germination resulted in a greater accumulation of GABA than germination alone. The treatment of cold stress at 0 °C for 1 h and germination for 72 h induced a maximum GABA content of 195.64 mg/100 g, 51.54% higher compared to the control, which was superior to any other treatment. We modified the metabolism of the GABA shunt to the orientation of GABA synthesis, in which the activity of glutamic acid decarboxylase and protease were stimulated. The total content of free amino acid indicated an upward trend as germination prolonged. The degradation of polyamines was partly promoted due to elevated diamine oxidase and polyamine oxidase activity, but the activity of amino-aldehyde dehydrogenase for the direct synthesis of GABA in the pathway was suppressed. The result implied that the GABA shunt might play a major role in enhancing GABA accumulation induced by cold stress and germination rather than the polyamines degradation pathway. This investigation provides a practical reference for GABA accumulation by germination under cold stress and a theoretical basis for the possible mechanism underlying the accelerating action.
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