Evidence map›Paper›PMID 36981057›Full record

ArticleFoods (Basel, Switzerland)2023

Protective Effect of Hawthorn Fruit Extract against High Fructose-Induced Oxidative Stress and Endoplasmic Reticulum Stress in Pancreatic β-Cells.

Hsiu-Man Lien, Hsin-Tang Lin, Shiau-Huei Huang, Yìng-Ru Chen, Chao-Lu Huang, Chia-Chang Chen, Charng-Cherng Chyau

Open access · goldFull text read
In one paragraph

Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. The Hawthorn (Foods (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hsiu-Man LienResearch Institute of Biotechnology, Hungkuang University, Shalu District, Taichung 43302, Taiwan.
Hsin-Tang LinGraduate Institute of Food Safety, National Chung Hsing University, 145, Xingda Road, Taichung 40227, Taiwan.
Shiau-Huei HuangResearch Institute of Biotechnology, Hungkuang University, Shalu District, Taichung 43302, Taiwan.
Yìng-Ru ChenResearch Institute of Biotechnology, Hungkuang University, Shalu District, Taichung 43302, Taiwan.
Chao-Lu HuangSYi Biotek, 2F, No. 26, Keyuan Rd., Xitun District, Taichung 40763, Taiwan.
Chia-Chang ChenSYi Biotek, 2F, No. 26, Keyuan Rd., Xitun District, Taichung 40763, Taiwan.
Charng-Cherng ChyauResearch Institute of Biotechnology, Hungkuang University, Shalu District, Taichung 43302, Taiwan.ORCID 0000-0001-6801-5573
Hungkuang University · TWNational Chung Hsing University · TW

Funding

Hungkuang University and SYI Biotechnology Co., Ltd. HK110-079 and HK109-077
6 · The paper itself

Abstract

Hyperglycemia has deleterious effects on pancreatic β-cells, causing dysfunction and insulin resistance that lead to diabetes mellitus (DM). The possible causes of injury can be caused by glucose- or fructose-induced oxidative and endoplasmic reticulum (ER) stress. Hawthorn (

Indexed as

Crataegus pinnatifidaendoplasmic reticulum (ER) stressgene expressionhawthorn fruithyperglycemiapancreatic β-cellpolyphenol-enriched extract

Identifiers

PMID36981057
PMCPMC10047983
OpenAlexW4323565622

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read89
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.