Evidence map›Paper›PMID 36981018›Full record

ArticleGenes2023

Therapeutic Targeting of P53: A Comparative Analysis of APR-246 and COTI-2 in Human Tumor Primary Culture 3-D Explants.

Adam J Nagourney, Joshua B Gipoor, Steven S Evans, Paulo D'Amora, Max S Duesberg, Paula J Bernard, Federico Francisco, Robert A Nagourney

Open access · goldFull text read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Adam J NagourneyNagourney Cancer Institute, 750 E. 29th Street, Long Beach, CA 90806, USA.
Joshua B GipoorNagourney Cancer Institute, 750 E. 29th Street, Long Beach, CA 90806, USA.
Steven S EvansNagourney Cancer Institute, 750 E. 29th Street, Long Beach, CA 90806, USA.
Paulo D'AmoraNagourney Cancer Institute, 750 E. 29th Street, Long Beach, CA 90806, USA.ORCID 0000-0003-2341-5340
Max S DuesbergNagourney Cancer Institute, 750 E. 29th Street, Long Beach, CA 90806, USA.
Paula J BernardNagourney Cancer Institute, 750 E. 29th Street, Long Beach, CA 90806, USA.
Federico FranciscoNagourney Cancer Institute, 750 E. 29th Street, Long Beach, CA 90806, USA.
Robert A NagourneyNagourney Cancer Institute, 750 E. 29th Street, Long Beach, CA 90806, USA.
Universidade Federal de São Paulo · BRUniversity of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsOvarian NeoplasmsCisplatinDoxorubicinFemaleHumansTumor Suppressor Protein p53Antineoplastic AgentsCisplatinDoxorubicinTumor Suppressor Protein p53anti-cancer drugAPR-246COTI-2TP53

Identifiers

PMID36981018
PMCPMC10048363
OpenAlexW4327954990

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read17
identifiers read4
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.