Evidence map›Paper›PMID 36981012›Full record

SynthesisGenes2023

Meta-Analysis of 49 SNPs Covering 25,446 Cases and 41,106 Controls Identifies Polymorphisms in Hormone Regulation and DNA Repair Genes Associated with Increased Endometrial Cancer Risk.

Agneesh Pratim Das, Nisha Chaudhary, Shrishty Tyagi, Subhash M Agarwal

Open access · goldFull text readMeta-Analysis
In one paragraph

Synthesis in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Agneesh Pratim DasBioinformatics Division, ICMR-National Institute of Cancer Prevention and Research, I-7, Sector-39, Noida 201301, India.
Nisha ChaudharyMultanimal Modi College, Chaudhary Charan Singh University, Modinagar 201204, India.
Shrishty TyagiMultanimal Modi College, Chaudhary Charan Singh University, Modinagar 201204, India.
Subhash M AgarwalBioinformatics Division, ICMR-National Institute of Cancer Prevention and Research, I-7, Sector-39, Noida 201301, India.
Chaudhary Charan Singh University · INNational Institute of Cancer Prevention and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometrial cancer (EC) is among the most common gynecological disorders globally. As single nucleotide polymorphisms (SNPs) play an important role in the causation of EC, therefore, a comprehensive meta-analysis of 49 SNPs covering 25,446 cases and 41,106 controls was performed to identify SNPs significantly associated with increased EC risk. PubMed was searched to identify case control studies and meta-analysis was performed to compute the pooled odds ratio (OR) at 95% confidence interval (CI). Cochran's Q-test and I

Indexed as

Endometrial NeoplasmsPolymorphism, Single NucleotideDNA RepairFemaleGenetic Predisposition to DiseaseHumansRiskXeroderma Pigmentosum Group D ProteinERCC2 protein, humanXeroderma Pigmentosum Group D ProteinDNA repairendometrial cancerhormone regulationmeta-analysisodds ratiosingle nucleotide polymorphism

Identifiers

PMID36981012
PMCPMC10048726
OpenAlexW4327955643

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read62
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.