Evidence map›Paper›PMID 36980815›Full record

ArticleGenes2023

Role of the Vitamin D Receptor (VDR) in the Pathogenesis of Osteoporosis: A Genetic, Epigenetic and Molecular Pilot Study.

Beatrice Gasperini, Virginia Veronica Visconti, Cinzia Ciccacci, Angela Falvino, Elena Gasbarra, Riccardo Iundusi, Maria Luisa Brandi, Annalisa Botta, Umberto Tarantino

Open access · goldFull text read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Epigenetic Patterns in Musculoskeletal Disease: Methylation ofCurrent issues in molecular biology · 2026
    Article
  3. Review
  4. Article
  5. Genes · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. TheInternational journal of molecular sciences · 2025
    Article
  13. Review on Advancement of AI in Nutrigenomics.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  14. Article
  15. Associations between theBiomedicines · 2024
    Article
  16. Article
  17. Methylation of the Vitamin D Receptor Gene in Human Disorders.International journal of molecular sciences · 2023
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Beatrice GasperiniDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Virginia Veronica ViscontiDepartment of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-4543-7770
Cinzia CiccacciUniCamillus-Saint Camillus International University of Health Sciences, 00131 Rome, Italy.ORCID 0000-0002-3995-7032
Angela FalvinoDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Elena GasbarraDepartment of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Riccardo IundusiDepartment of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Maria Luisa BrandiFIRMO Foundation, Via San Gallo 123, 50100 Florence, Italy.ORCID 0000-0002-8741-0592
Annalisa BottaDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Umberto TarantinoDepartment of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-0330-2189
University of Rome Tor Vergata · ITFondazione FADOI · ITSaint Camillus International University of Health and Medical Sciences · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vitamin D receptor (VDR) regulates bone development and calcium homeostasis, suggesting a central role in musculoskeletal diseases such as osteoporosis (OP). Several studies have examined the contribution of

Indexed as

Epigenesis, GeneticOsteoporosisReceptors, CalcitriolBone DensityHumansPilot ProjectsReceptors, CalcitriolVDR protein, humanbone mineral density (BMD)Cdx2DNA methylationFokIfragility fracture riskosteoporosispolymorphismTaqIvitamin D receptor (VDR)

Identifiers

PMID36980815
PMCPMC10048253
OpenAlexW4321496596

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read23
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.