Evidence map›Paper›PMID 36980810›Full record

ArticleGenes2023

Association of the

Yussef Esparza Guerrero, Maria Luisa Vazquez Villegas, Cesar Arturo Nava Valdivia, Juan Manuel Ponce Guarneros, Edsaul Emilio Perez Guerrero, Eli Efrain Gomez Ramirez, Melissa Ramirez Villafaña, Betsabe Contreras Haro, Alejandra Martinez Hernandez, Ernesto German Cardona Muñoz and 6 more

Open access · goldFull text read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. STAT4 gene polymorphism promotes progression of rheumatoid arthritis.Journal, genetic engineering & biotechnology · 2025
    Article
  5. Article
  6. Observational
  7. Genetic association betweenFrontiers in genetics · 2025
    Article
  8. Iranian journal of pathology · 2025
    Article
  9. Investigating the Link betweenInternational journal of molecular sciences · 2024
    Article
  10. Article
  11. STAT4 gene polymorphisms in human diseases.Frontiers in immunology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Yussef Esparza GuerreroPrograma de Doctorado en Farmacología, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.ORCID 0000-0001-6871-9052
Maria Luisa Vazquez VillegasDepartamento de Epidemiología, Unidad de Medicina Familiar No. 4, Instituto Mexicano del Seguro Social (IMSS), Guadalajara 44340, Mexico.
Cesar Arturo Nava ValdiviaDepartamento de Microbiología y Patología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Juan Manuel Ponce GuarnerosDepartamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.ORCID 0000-0001-5035-3347
Edsaul Emilio Perez GuerreroInstituto de Investigación en Ciencias Biomédicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.ORCID 0000-0002-0007-1824
Eli Efrain Gomez RamirezPrograma de Doctorado en Farmacología, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Melissa Ramirez VillafañaDepartamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Betsabe Contreras HaroUnidad de Investigación Biomédica 02, UMAE, Hospital de Especialidades, Centro Médico Nacional de Occidente, IMSS, Guadalajara 44349, Mexico.
Alejandra Martinez HernandezPrograma de Doctorado en Farmacología, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Ernesto German Cardona MuñozInstituto de Terapéutica Experimental y Clínica, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.ORCID 0000-0001-7868-667X
Ismael Nuño AranaDepartamento de Ciencias Biomédicas, Centro Universitario de Tonalá, Universidad de Guadalajara, Guadalajara 45400, Mexico.ORCID 0000-0002-0386-1004
Sergio Gabriel Gallardo MoyaPrograma de Doctorado en Farmacología, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Alfredo CelisInstituto Regional de Investigación en Salud Pública, Programa de Doctorado y Coordinación del Programa de Doctorado en Salud Pública, Departamento de Salud Pública, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Laura Gonzalez LopezPrograma de Doctorado en Farmacología, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.ORCID 0000-0002-6517-6344
Jorge Ivan Gamez NavaPrograma de Doctorado en Farmacología, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Ana Miriam Saldaña CruzInstituto de Terapéutica Experimental y Clínica, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Mexico.
Universidad de Guadalajara · MXMexican Social Security Institute · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STAT4 plays an important role in disease activity in SLE patients. STAT4 particles have the capacity to activate the transcription of genes associated with the production of TH1 and Th17 lymphocytes, with a greater predominance on the production of IFN-γ and IL-17A. The presence of variants in

Indexed as

Autoimmune DiseasesInterferon-gammaLupus Erythematosus, SystemicSTAT4 Transcription FactorAllelesCase-Control StudiesChild, PreschoolCytokinesGenetic Predisposition to DiseaseHumansInterleukin-17Polymorphism, Single NucleotideCytokinesInterferon-gammaInterleukin-17STAT4 protein, humanSTAT4 Transcription FactorIFN-gammapolymorphismSTAT4systemic lupus erythematosus

Identifiers

PMID36980810
PMCPMC10048585
OpenAlexW4321496733

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read37
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.