Evidence map›Paper›PMID 36980793›Full record

ArticleCancers2023

Deep Learning Approach to Classify Cutaneous Melanoma in a Whole Slide Image.

Meng Li, Makoto Abe, Shigeo Nakano, Masayuki Tsuneki

Open access · goldFull text read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Meng LiMedmain Research, Medmain Inc., Fukuoka 810-0042, Japan.
Makoto AbeDepartment of Pathology, Tochigi Cancer Center, 4-9-13 Yohnan, Utsunomiya 320-0834, Japan.ORCID 0009-0000-3674-2151
Shigeo NakanoDepartment of Surgical Pathology, Tokyo Shinagawa Hospital, 6-3-22 Higashi-Ooi, Shinagawa, Tokyo 140-8522, Japan.
Masayuki TsunekiMedmain Research, Medmain Inc., Fukuoka 810-0042, Japan.ORCID 0000-0003-3409-5485
New Tokyo Hospital · JPTochigi Cancer Center · JP

Funding

New Energy and Industrial Technology Development Organization JPNP14012
6 · The paper itself

Abstract

Although the histopathological diagnosis of cutaneous melanocytic lesions is fairly accurate and reliable among experienced surgical pathologists, it is not perfect in every case (especially melanoma). Microscopic examination-clinicopathological correlation is the gold standard for the definitive diagnosis of melanoma. Pathologists may encounter diagnostic controversies when melanoma closely mimics Spitz's nevus or blue nevus, exhibits amelanotic histopathology, or is in situ. It would be beneficial if diagnosing cutaneous melanocytic lesions can be automated by using deep learning, particularly when assisting surgical pathologists with their workloads. In this preliminary study, we investigated the application of deep learning for classifying cutaneous melanoma in whole-slide images (WSIs). We trained models via weakly supervised learning using a dataset of 66 WSIs (33 melanomas and 33 non-melanomas). We evaluated the models on a test set of 90 WSIs (40 melanomas and 50 non-melanomas), achieving ROC-AUC at 0.821 for the WSI level and 0.936 for the tile level by the best model.

Indexed as

cancer screeningdeep learningmelanomawhole slide image

Identifiers

PMID36980793
PMCPMC10047087
OpenAlexW4353067165

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read19
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.